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A new monoterpene glycoside and antibacterial monoterpene glycosides from Paeonia suffruticosa

  • Ren Bo An
  • , Hyun Chul Kim
  • , Sung Hee Lee
  • , Gil Saeng Jeong
  • , Dong Hwan Sohn
  • , Hyun Park
  • , Dong Yeul Kwon
  • , John Hwa Lee
  • , Youn Chul Kim*
  • *Corresponding author for this work
  • Wonkwang University
  • Yanbian University

Research output: Contribution to journalJournal articlepeer-review

Abstract

Antibacterial activity-guided fractionation of the CHCl3-MeOH (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to 500 μg/mL against eighteen pathogenic microorganisms of concern for public health or zoonosis.

Original languageEnglish
Pages (from-to)815-820
Number of pages6
JournalArchives of Pharmacal Research
Volume29
Issue number10
DOIs
StatePublished - 2006.10.31

Keywords

  • 6-O-Vanillyoxypaeoniflorin
  • Antibacterial
  • Galloyl-oxypaeoniflorin
  • Monoterpene glycoside
  • Mudanpioside-H
  • Paeonia suffruticosa

Quacquarelli Symonds(QS) Subject Topics

  • Medicine
  • Engineering - Petroleum
  • Pharmacy & Pharmacology
  • Chemistry

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