A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea

Hyun Ah Jung; Hae Young Chung; Jee H. Jung; Jae Sue Choi

doi:10.1248/cpb.52.157

A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea

Hyun Ah Jung
, Hae Young Chung
, Jee H. Jung
, Jae Sue Choi^*

^*Corresponding author for this work

Department of Food Science and Human Nutrition

Pukyong National University
Pusan National University

Research output: Contribution to journal › Journal article › peer-review

31 Scopus citations

Abstract

A new triterpenoid, 2α,3α,24-trihydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2α-hydroxyursolic acid (2), 2α,3α,24- trihydroxyurs-12-en-28-oic acid (3), and 2α,3α,19α,24- tetrahydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3 - 5 showed ONOO^- scavenging activity, whereas compounds 1 and 2 were virtually inactive.

Original language	English
Pages (from-to)	157-159
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	52
Issue number	1
DOIs	https://doi.org/10.1248/cpb.52.157
State	Published - 2004.01

Keywords

2α,3α, 24-trihydroxyurs-12-en-28-oic acid-28-o-β-D-glucopyranosyl ester
ONOO scavenging activity
Prunus serrulata var. spontanea
Rosaceae
Triterpenoids

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title = "A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea",

abstract = "A new triterpenoid, 2α,3α,24-trihydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2α-hydroxyursolic acid (2), 2α,3α,24- trihydroxyurs-12-en-28-oic acid (3), and 2α,3α,19α,24- tetrahydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3 - 5 showed ONOO- scavenging activity, whereas compounds 1 and 2 were virtually inactive.",

keywords = "2α,3α, 24-trihydroxyurs-12-en-28-oic acid-28-o-β-D-glucopyranosyl ester, ONOO scavenging activity, Prunus serrulata var. spontanea, Rosaceae, Triterpenoids",

author = "Jung, \{Hyun Ah\} and Chung, \{Hae Young\} and Jung, \{Jee H.\} and Choi, \{Jae Sue\}",

year = "2004",

month = jan,

doi = "10.1248/cpb.52.157",

language = "English",

volume = "52",

pages = "157--159",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

number = "1",

}

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T1 - A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea

AU - Jung, Hyun Ah

AU - Chung, Hae Young

AU - Jung, Jee H.

AU - Choi, Jae Sue

PY - 2004/1

Y1 - 2004/1

N2 - A new triterpenoid, 2α,3α,24-trihydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2α-hydroxyursolic acid (2), 2α,3α,24- trihydroxyurs-12-en-28-oic acid (3), and 2α,3α,19α,24- tetrahydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3 - 5 showed ONOO- scavenging activity, whereas compounds 1 and 2 were virtually inactive.

AB - A new triterpenoid, 2α,3α,24-trihydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2α-hydroxyursolic acid (2), 2α,3α,24- trihydroxyurs-12-en-28-oic acid (3), and 2α,3α,19α,24- tetrahydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3 - 5 showed ONOO- scavenging activity, whereas compounds 1 and 2 were virtually inactive.

KW - 2α,3α, 24-trihydroxyurs-12-en-28-oic acid-28-o-β-D-glucopyranosyl ester

KW - ONOO scavenging activity

KW - Prunus serrulata var. spontanea

KW - Rosaceae

KW - Triterpenoids

UR - https://www.scopus.com/pages/publications/3543127678

U2 - 10.1248/cpb.52.157

DO - 10.1248/cpb.52.157

M3 - Journal article

C2 - 14709888

AN - SCOPUS:3543127678

SN - 0009-2363

VL - 52

SP - 157

EP - 159

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 1

ER -

A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea

Abstract

Keywords

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