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A phenolic glucoside isolated from Prunus serrulata var. spontanea and its peroxynitrite scavenging activity

  • Ah Jung Hyun
  • , Young Chung Hae
  • , Sik Kang Sam
  • , Kyung Hyun Sook
  • , Sook Kang Hye
  • , Sue Choi Jae*
  • *Corresponding author for this work
  • Pukyong National University
  • Pusan National University
  • Seoul National University

Research output: Contribution to journalJournal articlepeer-review

Abstract

A new phenolic glucoside (1), pursargentoside, was isolated from the leaves of Prunus serrulata var. spontanea, along with three other known compounds, orobol 7-O-glucoside (2), 1β, 2α, 3α, 24-tetrahydroxy-urs-12- en-28-oic acid (3), and chlorogenic acid (4). The structure of pursargentoside (1) was identified by spectroscopic data analysis including 1D and 2D NMR spectroscopy, as 2-O-β-(6′-benzoyl)-glucopyranosyl o-(Z)-coumaric acid. Compounds 1, 2, and 4 exhibited ONOO. scavenging activity, whereas compound 3 was determined to be virtually inactive.

Original languageEnglish
Pages (from-to)1127-1130
Number of pages4
JournalArchives of Pharmacal Research
Volume28
Issue number10
DOIs
StatePublished - 2005.10.31

Keywords

  • Peroxynitrite scavenging activity
  • Phenolic glucoside
  • Prunus serrulata var. spontanea
  • Pursargentoside
  • Rosaceae

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