An antibacterial compound against Pasteurella haemolytica produced by Streptomyces sp. 51086

Hee Chol Kang; In Ja Ryoo; Bong Sik Yun; Yong Soo Jeon; Ick Dong Yoo

An antibacterial compound against Pasteurella haemolytica produced by Streptomyces sp. 51086

Hee Chol Kang
, In Ja Ryoo
, Bong Sik Yun
, Yong Soo Jeon
, Ick Dong Yoo^*

^*Corresponding author for this work

Environmental Biotechnology

Korea Research Institute of Bioscience and Biotechnology
Animal and Plant Quarantine Agency

Research output: Contribution to journal › Journal article › peer-review

Abstract

Pasteurella haemolytica is well known to cause severe pneumonia, consolidation and oedema of the lung, and fibrinous pleurisy under the stress and infection of virus in the cattle. In the course of our screening for antimicrobial agents against P. haemolytica, compound 51086 has been isolated from the fermentation broth of Streptomyces sp. 51086. The compound 51086 was purified by SiO₂, Sephadex LH-20 and ODS column chromatographies and HPLC, subsequently. The structure of compound 51086 was determined as hygromycin A by combination of 1(H) NMR, 13(C) NMR, HMBC, and ESI-MS. This compound showed significant antibacterial activity against P. haemolytica and P. multocida.

Original language	English
Pages (from-to)	339-343
Number of pages	5
Journal	Korean Journal of Applied Microbiology and Biotechnology
Volume	27
Issue number	4
State	Published - 1999.08

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Antimicrobial activity
Hygromycin A
Pasteurella haemolytica
Structure determination

Cite this

@article{cdc13a88f90b4c878f1fbdaa6ba74117,

title = "An antibacterial compound against Pasteurella haemolytica produced by Streptomyces sp. 51086",

abstract = "Pasteurella haemolytica is well known to cause severe pneumonia, consolidation and oedema of the lung, and fibrinous pleurisy under the stress and infection of virus in the cattle. In the course of our screening for antimicrobial agents against P. haemolytica, compound 51086 has been isolated from the fermentation broth of Streptomyces sp. 51086. The compound 51086 was purified by SiO2, Sephadex LH-20 and ODS column chromatographies and HPLC, subsequently. The structure of compound 51086 was determined as hygromycin A by combination of 1(H) NMR, 13(C) NMR, HMBC, and ESI-MS. This compound showed significant antibacterial activity against P. haemolytica and P. multocida.",

keywords = "Antimicrobial activity, Hygromycin A, Pasteurella haemolytica, Structure determination",

author = "Kang, \{Hee Chol\} and Ryoo, \{In Ja\} and Yun, \{Bong Sik\} and Jeon, \{Yong Soo\} and Yoo, \{Ick Dong\}",

year = "1999",

month = aug,

language = "English",

volume = "27",

pages = "339--343",

journal = "Korean Journal of Applied Microbiology and Biotechnology",

issn = "0257-2389",

number = "4",

}

TY - JOUR

T1 - An antibacterial compound against Pasteurella haemolytica produced by Streptomyces sp. 51086

AU - Kang, Hee Chol

AU - Ryoo, In Ja

AU - Yun, Bong Sik

AU - Jeon, Yong Soo

AU - Yoo, Ick Dong

PY - 1999/8

Y1 - 1999/8

N2 - Pasteurella haemolytica is well known to cause severe pneumonia, consolidation and oedema of the lung, and fibrinous pleurisy under the stress and infection of virus in the cattle. In the course of our screening for antimicrobial agents against P. haemolytica, compound 51086 has been isolated from the fermentation broth of Streptomyces sp. 51086. The compound 51086 was purified by SiO2, Sephadex LH-20 and ODS column chromatographies and HPLC, subsequently. The structure of compound 51086 was determined as hygromycin A by combination of 1(H) NMR, 13(C) NMR, HMBC, and ESI-MS. This compound showed significant antibacterial activity against P. haemolytica and P. multocida.

AB - Pasteurella haemolytica is well known to cause severe pneumonia, consolidation and oedema of the lung, and fibrinous pleurisy under the stress and infection of virus in the cattle. In the course of our screening for antimicrobial agents against P. haemolytica, compound 51086 has been isolated from the fermentation broth of Streptomyces sp. 51086. The compound 51086 was purified by SiO2, Sephadex LH-20 and ODS column chromatographies and HPLC, subsequently. The structure of compound 51086 was determined as hygromycin A by combination of 1(H) NMR, 13(C) NMR, HMBC, and ESI-MS. This compound showed significant antibacterial activity against P. haemolytica and P. multocida.

KW - Antimicrobial activity

KW - Hygromycin A

KW - Pasteurella haemolytica

KW - Structure determination

UR - https://www.scopus.com/pages/publications/0032857751

M3 - Journal article

AN - SCOPUS:0032857751

SN - 0257-2389

VL - 27

SP - 339

EP - 343

JO - Korean Journal of Applied Microbiology and Biotechnology

JF - Korean Journal of Applied Microbiology and Biotechnology

IS - 4

ER -

An antibacterial compound against Pasteurella haemolytica produced by Streptomyces sp. 51086

Abstract

UN SDGs

Keywords

Other files and links

Fingerprint

Cite this