Antifungal substances from Streptomyces sp. A3265 antagonistic to plant pathogenic fungi

  • Nguyen Van Minh
  • , E. Eum Woo
  • , Ji Yul Kim
  • , Dae Won Kim
  • , Byung Soon Hwang
  • , Yoon Ju Lee
  • , In Kyoung Lee
  • , Bong Sik Yun*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

Abstract

In a previous study, we identified a Streptomyces sp., A3265, as exhibiting potent antifungal activity against various plant pathogenic fungi, including Botrytis cinerea, Colletotrichum gloeosporioides, and Rhizoctonia solani. This strain also exhibited a biocontrolling effect against ginseng root rot and damping-off disease, common diseases of ginseng and other crops. In this study, we isolated two antifungal substances responsible for this biocontrolling effect via Diaion HP-20 and Sephadex LH-20 column chromatography, medium pressure liquid chromatography, and high-performance liquid chromatography. These compounds were identified as guanidylfungin A and methyl guanidylfungin A by spectroscopic methods. These compounds exhibited potent antimicrobial activity against various plant pathogenic fungi as well as against bacteria.

Original languageEnglish
Pages (from-to)333-338
Number of pages6
JournalMycobiology
Volume43
Issue number3
DOIs
StatePublished - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 2 - Zero Hunger
    SDG 2 Zero Hunger

Keywords

  • Biocontrol agent
  • Damping-off
  • Guanidylfungin
  • Streptomyces sp. A3265

Quacquarelli Symonds(QS) Subject Topics

  • Medicine
  • Biological Sciences

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