Application of Gellan Gum-Based Scaffold for Regenerative Medicine

  • Joo Hee Choi
  • , Wonchan Lee
  • , Cheolui Song
  • , Byung Kwan Moon
  • , Sun jung Yoon
  • , Nuno M. Neves
  • , Rui L. Reis
  • , Gilson Khang*
  • *Corresponding author for this work

Research output: Contribution to conferenceChapterpeer-review

Abstract

Gellan gum (GG) is a linear microbial exopolysaccharide which is derived naturally by the fermentation process of Pseudomonas elodea. Application of GG in tissue engineering and regeneration medicine (TERM) is already over 10 years and has shown great potential. Although this biomaterial has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations, a variety of modification methods have been suggested due to some disadvantages such as mechanical properties, high gelation temperature, and lack of attachment sites. In this review, the application of GG-based scaffold for tissue engineering and approaches to improve GG properties are discussed. Furthermore, a recent trend and future perspective of GG-based scaffold are highlighted.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages15-37
Number of pages23
DOIs
StatePublished - 2020

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1249
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Application
  • Gellan gum
  • Nature derived
  • Regeneration
  • Scaffold
  • Tissue engineering

Quacquarelli Symonds(QS) Subject Topics

  • Biological Sciences

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