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CagA-producing Helicobacter pylori and increased risk of gastric cancer: A nested case-control study in Korea

  • J. Gwack
  • , A. Shin
  • , C. S. Kim
  • , K. P. Ko
  • , Y. Kim
  • , J. K. Jun
  • , J. Bae
  • , S. K. Park
  • , Y. C. Hong
  • , D. Kang
  • , S. H. Chang
  • , H. R. Shin
  • , K. Y. Yoo*
  • *Corresponding author for this work
  • Seoul National University
  • Vanderbilt University
  • Konkuk University
  • National Cancer Center Korea

Research output: Contribution to journalJournal articlepeer-review

Abstract

In a nested-case control study of 100 cases of gastric cancer and 400 matched controls in relation to virulence factors of Helicobacter pylori in a Korean cohort, CagA seropositivity was significantly associated with a higher risk of gastric cancer among H. pylori-infected subjects (OR=3.57, 95% CI 1.05-12.14).

Original languageEnglish
Pages (from-to)639-641
Number of pages3
JournalBritish Journal of Cancer
Volume95
Issue number5
DOIs
StatePublished - 2006.09.4

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • CagA
  • Cohort study
  • Gastric cancer
  • Helicobacter pylori
  • Korea

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