Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor

Krishna Prasad Sharma; Miyeon Shin; Ganesh Prasad Awasthi; Milan Babu Poudel; Han Joo Kim; Changho Yu

doi:10.1016/j.ijbiomac.2022.02.142

Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor

Krishna Prasad Sharma
, Miyeon Shin
, Ganesh Prasad Awasthi
, Milan Babu Poudel
, Han Joo Kim^*
, Changho Yu^*

^*Corresponding author for this work

IT Convergence Mechatronics Engineering

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

46 Scopus citations

Abstract

In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer. Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance. The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM⁻¹ cm⁻² with an excellent linear response. Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum. The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.

Original language	English
Pages (from-to)	708-717
Number of pages	10
Journal	International Journal of Biological Macromolecules
Volume	206
DOIs	https://doi.org/10.1016/j.ijbiomac.2022.02.142
State	Published - 2022.05.1

Keywords

Chitosan
Copper sulfide
Glucose
Hydrothermal method
Sensitivity

Quacquarelli Symonds(QS) Subject Topics

Biological Sciences

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10.1016/j.ijbiomac.2022.02.142

Cite this

@article{01604289c01949649373544b35811a14,

title = "Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor",

abstract = "In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer. Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance. The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM−1 cm−2 with an excellent linear response. Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum. The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.",

keywords = "Chitosan, Copper sulfide, Glucose, Hydrothermal method, Sensitivity",

author = "Sharma, \{Krishna Prasad\} and Miyeon Shin and Awasthi, \{Ganesh Prasad\} and Poudel, \{Milan Babu\} and Kim, \{Han Joo\} and Changho Yu",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = may,

day = "1",

doi = "10.1016/j.ijbiomac.2022.02.142",

language = "English",

volume = "206",

pages = "708--717",

journal = "International Journal of Biological Macromolecules",

issn = "0141-8130",

}

TY - JOUR

T1 - Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor

AU - Sharma, Krishna Prasad

AU - Shin, Miyeon

AU - Awasthi, Ganesh Prasad

AU - Poudel, Milan Babu

AU - Kim, Han Joo

AU - Yu, Changho

PY - 2022/5/1

Y1 - 2022/5/1

N2 - In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer. Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance. The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM−1 cm−2 with an excellent linear response. Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum. The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.

AB - In this study, N and S co-doped chitosan polymer matrix-derived composite (CuS/NSC) was synthesized via a one-step hydrothermal technique using a low-cost copper complex of chitosan polymer. Cyclic voltammetry and chronoamperometry revealed excellent electrocatalytic performance. The glucose sensor exhibited a linear range of 160 μM to 11.76 mM, a low detection limit 2.72 μM and a sensitivity of 13.62 mA mM−1 cm−2 with an excellent linear response. Furthermore, the sensor also displayed selectivity for glucose over potential interfering agents and exhibited a satisfactory recovery percentage using real sample in human serum. The results demonstrate that, CuS/NSC is an efficient nanocomposite material for non-enzymatic glucose sensors and is applicable for glucose detection in biological fluids.

KW - Chitosan

KW - Copper sulfide

KW - Glucose

KW - Hydrothermal method

KW - Sensitivity

UR - https://www.scopus.com/pages/publications/85125757551

U2 - 10.1016/j.ijbiomac.2022.02.142

DO - 10.1016/j.ijbiomac.2022.02.142

M3 - Journal article

C2 - 35231535

AN - SCOPUS:85125757551

SN - 0141-8130

VL - 206

SP - 708

EP - 717

JO - International Journal of Biological Macromolecules

JF - International Journal of Biological Macromolecules

ER -

Chitosan polymer matrix-derived nanocomposite (CuS/NSC) for non-enzymatic electrochemical glucose sensor

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

Access to Document

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