Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

B. S. Yun; I. K. Lee; I. J. Ryoo; I. D. Yoo

doi:10.1021/np0100946

Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

B. S. Yun
, I. K. Lee
, I. J. Ryoo
, I. D. Yoo^*

^*Corresponding author for this work

Environmental Biotechnology

Korea Research Institute of Bioscience and Biotechnology

Research output: Contribution to journal › Journal article › peer-review

127 Scopus citations

Abstract

A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC₅₀ values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.

Original language	English
Pages (from-to)	1238-1240
Number of pages	3
Journal	Journal of Natural Products
Volume	64
Issue number	9
DOIs	https://doi.org/10.1021/np0100946
State	Published - 2001

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title = "Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus",

abstract = "A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC50 values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.",

author = "Yun, \{B. S.\} and Lee, \{I. K.\} and Ryoo, \{I. J.\} and Yoo, \{I. D.\}",

year = "2001",

doi = "10.1021/np0100946",

language = "English",

volume = "64",

pages = "1238--1240",

journal = "Journal of Natural Products",

issn = "0163-3864",

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TY - JOUR

T1 - Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

AU - Yun, B. S.

AU - Lee, I. K.

AU - Ryoo, I. J.

AU - Yoo, I. D.

PY - 2001

Y1 - 2001

N2 - A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC50 values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.

AB - A previously undescribed coumarin and a new coumarino-lignan, together with the known compounds scopoletin and cleomiscosins A, C, and D, have been isolated from the root bark of Hibiscus syriacus, and their structures were assigned on the basis of various spectral studies. The coumarin analogue and scopoletin inhibited monoamine oxidase with moderate IC50 values. The new coumarino-lignan and cleomiscosin C showed lipid peroxidation inhibitory activity comparable to vitamin E.

UR - https://www.scopus.com/pages/publications/0034786818

U2 - 10.1021/np0100946

DO - 10.1021/np0100946

M3 - Journal article

C2 - 11575966

AN - SCOPUS:0034786818

SN - 0163-3864

VL - 64

SP - 1238

EP - 1240

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 9

ER -

Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

Abstract

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