Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica

Dae Won Ki; Seong Eun Kim; Ji Yul Kim; Ja Gyeong Song; Byung Soon Hwang; In Kyoung Lee; Bong Sik Yun

doi:10.1007/s11418-021-01592-0

Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica

Dae Won Ki
, Seong Eun Kim
, Ji Yul Kim
, Ja Gyeong Song
, Byung Soon Hwang
, In Kyoung Lee
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Research output: Contribution to journal › Journal article › peer-review

12 Scopus citations

Abstract

Four new isoindolinone derivatives, daldinans D‒G (3‒6), together with two known compounds, daldinans A and B (1 and 2), were isolated from the stroma of the ascomycete Daldinia concentrica. Chemical structures of the isolated compounds were determined by spectroscopic methods. All of these compounds exhibited antioxidant activities with IC₅₀ values of 3.21 to 39.67 µM in the 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay.

Original language	English
Pages (from-to)	476-481
Number of pages	6
Journal	Journal of Natural Medicines
Volume	76
Issue number	2
DOIs	https://doi.org/10.1007/s11418-021-01592-0
State	Published - 2022.03

Keywords

Antioxidant
Daldinan
Daldinia concentrica
Isoindolinone derivatives
Mushroom

Quacquarelli Symonds(QS) Subject Topics

Medicine

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10.1007/s11418-021-01592-0

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title = "Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica",

abstract = "Four new isoindolinone derivatives, daldinans D‒G (3‒6), together with two known compounds, daldinans A and B (1 and 2), were isolated from the stroma of the ascomycete Daldinia concentrica. Chemical structures of the isolated compounds were determined by spectroscopic methods. All of these compounds exhibited antioxidant activities with IC50 values of 3.21 to 39.67 µM in the 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay.",

keywords = "Antioxidant, Daldinan, Daldinia concentrica, Isoindolinone derivatives, Mushroom",

author = "Ki, \{Dae Won\} and Kim, \{Seong Eun\} and Kim, \{Ji Yul\} and Song, \{Ja Gyeong\} and Hwang, \{Byung Soon\} and Lee, \{In Kyoung\} and Yun, \{Bong Sik\}",

note = "Publisher Copyright: {\textcopyright} 2021, The Japanese Society of Pharmacognosy.",

year = "2022",

month = mar,

doi = "10.1007/s11418-021-01592-0",

language = "English",

volume = "76",

pages = "476--481",

journal = "Journal of Natural Medicines",

issn = "1340-3443",

number = "2",

}

TY - JOUR

T1 - Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica

AU - Ki, Dae Won

AU - Kim, Seong Eun

AU - Kim, Ji Yul

AU - Song, Ja Gyeong

AU - Hwang, Byung Soon

AU - Lee, In Kyoung

AU - Yun, Bong Sik

PY - 2022/3

Y1 - 2022/3

N2 - Four new isoindolinone derivatives, daldinans D‒G (3‒6), together with two known compounds, daldinans A and B (1 and 2), were isolated from the stroma of the ascomycete Daldinia concentrica. Chemical structures of the isolated compounds were determined by spectroscopic methods. All of these compounds exhibited antioxidant activities with IC50 values of 3.21 to 39.67 µM in the 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay.

AB - Four new isoindolinone derivatives, daldinans D‒G (3‒6), together with two known compounds, daldinans A and B (1 and 2), were isolated from the stroma of the ascomycete Daldinia concentrica. Chemical structures of the isolated compounds were determined by spectroscopic methods. All of these compounds exhibited antioxidant activities with IC50 values of 3.21 to 39.67 µM in the 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay.

KW - Antioxidant

KW - Daldinan

KW - Daldinia concentrica

KW - Isoindolinone derivatives

KW - Mushroom

UR - https://www.scopus.com/pages/publications/85123293826

U2 - 10.1007/s11418-021-01592-0

DO - 10.1007/s11418-021-01592-0

M3 - Journal article

C2 - 35034277

AN - SCOPUS:85123293826

SN - 1340-3443

VL - 76

SP - 476

EP - 481

JO - Journal of Natural Medicines

JF - Journal of Natural Medicines

IS - 2

ER -

Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

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