Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis

Lee Su Ha; Dae Won Ki; Ji Yul Kim; Dae Cheol Choi; In Kyoung Lee; Bong Sik Yun

doi:10.1038/s41429-021-00426-1

Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis

Lee Su Ha
, Dae Won Ki
, Ji Yul Kim
, Dae Cheol Choi
, In Kyoung Lee
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

15 Scopus citations

Abstract

In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.

Original language	English
Pages (from-to)	538-541
Number of pages	4
Journal	Journal of Antibiotics
Volume	74
Issue number	8
DOIs	https://doi.org/10.1038/s41429-021-00426-1
State	Published - 2021.08

Quacquarelli Symonds(QS) Subject Topics

Pharmacy & Pharmacology

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10.1038/s41429-021-00426-1

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title = "Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis",

abstract = "In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.",

author = "Ha, \{Lee Su\} and Ki, \{Dae Won\} and Kim, \{Ji Yul\} and Choi, \{Dae Cheol\} and Lee, \{In Kyoung\} and Yun, \{Bong Sik\}",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to the Japan Antibiotics Research Association.",

year = "2021",

month = aug,

doi = "10.1038/s41429-021-00426-1",

language = "English",

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AU - Ha, Lee Su

AU - Ki, Dae Won

AU - Kim, Ji Yul

AU - Choi, Dae Cheol

AU - Lee, In Kyoung

AU - Yun, Bong Sik

PY - 2021/8

Y1 - 2021/8

N2 - In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.

AB - In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.

UR - https://www.scopus.com/pages/publications/85106709847

U2 - 10.1038/s41429-021-00426-1

DO - 10.1038/s41429-021-00426-1

M3 - Journal article

C2 - 34045694

AN - SCOPUS:85106709847

SN - 0021-8820

VL - 74

SP - 538

EP - 541

JO - Journal of Antibiotics

JF - Journal of Antibiotics

IS - 8

ER -

Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis

Abstract

Quacquarelli Symonds(QS) Subject Topics

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