Detection of small brain metastases at 3 T: Comparing the diagnostic performances of contrast-enhanced T1-weighted SPACE, MPRAGE, and 2D FLASH imaging

Hyo Sung Kwak; Seungbae Hwang; Gyung Ho Chung; Ji Soo Song; Eun Jung Choi

doi:10.1016/j.clinimag.2015.02.010

Detection of small brain metastases at 3 T: Comparing the diagnostic performances of contrast-enhanced T1-weighted SPACE, MPRAGE, and 2D FLASH imaging

Hyo Sung Kwak
, Seungbae Hwang^*
, Gyung Ho Chung
, Ji Soo Song
, Eun Jung Choi

^*Corresponding author for this work

Department of Medicine

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

22 Scopus citations

Abstract

The aim of this study was to compare the diagnostic performance of contrast-enhanced T1-weighted sampling perfection with application-optimized contrasts using different flip angle evolutions (SPACE), magnetization-prepared rapid gradient-echo (MPRAGE), and two-dimensional (2D) fast low angle shot (FLASH) for the detection of small brain metastases. Twelve patients who had brain metastases less than 10 mm in diameter were enrolled. The diagnostic performance was evaluated using alternative free-response receiver operating characteristic analysis. Sensitivity and positive predictive value were also calculated. The mean A_z and sensitivities of SPACE for all observers were significantly higher than those of MPRAGE and 2D FLASH.

Original language	English
Pages (from-to)	571-575
Number of pages	5
Journal	Clinical Imaging
Volume	39
Issue number	4
DOIs	https://doi.org/10.1016/j.clinimag.2015.02.010
State	Published - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

3 Tesla
Brain
Magnetic resonance imaging
Neoplasm metastasis
SPACE

Quacquarelli Symonds(QS) Subject Topics

Medicine

Access to Document

10.1016/j.clinimag.2015.02.010

Cite this

@article{81e2598dee4741c3bfeadf9dd0a59541,

title = "Detection of small brain metastases at 3 T: Comparing the diagnostic performances of contrast-enhanced T1-weighted SPACE, MPRAGE, and 2D FLASH imaging",

abstract = "The aim of this study was to compare the diagnostic performance of contrast-enhanced T1-weighted sampling perfection with application-optimized contrasts using different flip angle evolutions (SPACE), magnetization-prepared rapid gradient-echo (MPRAGE), and two-dimensional (2D) fast low angle shot (FLASH) for the detection of small brain metastases. Twelve patients who had brain metastases less than 10 mm in diameter were enrolled. The diagnostic performance was evaluated using alternative free-response receiver operating characteristic analysis. Sensitivity and positive predictive value were also calculated. The mean Az and sensitivities of SPACE for all observers were significantly higher than those of MPRAGE and 2D FLASH.",

keywords = "3 Tesla, Brain, Magnetic resonance imaging, Neoplasm metastasis, SPACE",

author = "Kwak, \{Hyo Sung\} and Seungbae Hwang and Chung, \{Gyung Ho\} and Song, \{Ji Soo\} and Choi, \{Eun Jung\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

doi = "10.1016/j.clinimag.2015.02.010",

language = "English",

volume = "39",

pages = "571--575",

journal = "Clinical Imaging",

issn = "0899-7071",

number = "4",

}

TY - JOUR

T1 - Detection of small brain metastases at 3 T

T2 - Comparing the diagnostic performances of contrast-enhanced T1-weighted SPACE, MPRAGE, and 2D FLASH imaging

AU - Kwak, Hyo Sung

AU - Hwang, Seungbae

AU - Chung, Gyung Ho

AU - Song, Ji Soo

AU - Choi, Eun Jung

PY - 2015

Y1 - 2015

N2 - The aim of this study was to compare the diagnostic performance of contrast-enhanced T1-weighted sampling perfection with application-optimized contrasts using different flip angle evolutions (SPACE), magnetization-prepared rapid gradient-echo (MPRAGE), and two-dimensional (2D) fast low angle shot (FLASH) for the detection of small brain metastases. Twelve patients who had brain metastases less than 10 mm in diameter were enrolled. The diagnostic performance was evaluated using alternative free-response receiver operating characteristic analysis. Sensitivity and positive predictive value were also calculated. The mean Az and sensitivities of SPACE for all observers were significantly higher than those of MPRAGE and 2D FLASH.

AB - The aim of this study was to compare the diagnostic performance of contrast-enhanced T1-weighted sampling perfection with application-optimized contrasts using different flip angle evolutions (SPACE), magnetization-prepared rapid gradient-echo (MPRAGE), and two-dimensional (2D) fast low angle shot (FLASH) for the detection of small brain metastases. Twelve patients who had brain metastases less than 10 mm in diameter were enrolled. The diagnostic performance was evaluated using alternative free-response receiver operating characteristic analysis. Sensitivity and positive predictive value were also calculated. The mean Az and sensitivities of SPACE for all observers were significantly higher than those of MPRAGE and 2D FLASH.

KW - 3 Tesla

KW - Brain

KW - Magnetic resonance imaging

KW - Neoplasm metastasis

KW - SPACE

UR - https://www.scopus.com/pages/publications/84954197196

U2 - 10.1016/j.clinimag.2015.02.010

DO - 10.1016/j.clinimag.2015.02.010

M3 - Journal article

C2 - 25770904

AN - SCOPUS:84954197196

SN - 0899-7071

VL - 39

SP - 571

EP - 575

JO - Clinical Imaging

JF - Clinical Imaging

IS - 4

ER -

Detection of small brain metastases at 3 T: Comparing the diagnostic performances of contrast-enhanced T1-weighted SPACE, MPRAGE, and 2D FLASH imaging

Abstract

UN SDGs

Keywords

Quacquarelli Symonds(QS) Subject Topics

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