Detection of structure-switching in G-quadruplexes using end-stacking ability

Young Jun Seo; Il Joon Lee; Byeang Hyean Kim

doi:10.1016/j.bmcl.2008.06.033

Detection of structure-switching in G-quadruplexes using end-stacking ability

Young Jun Seo
, Il Joon Lee
, Byeang Hyean Kim^*

^*Corresponding author for this work

Department of Chemistry

Pohang University of Science and Technology

Research output: Contribution to journal › Journal article › peer-review

13 Scopus citations

Abstract

G-quadruplex-forming ODNs containing nonpolar aromatic fluorophore moiety, A^PY at the dangling ends undergo π-stacking on surface of G-quadruplex, and the fluorescence change can be used to distinguish the structure-switching between the mixed parallel/antiparallel structure and antiparallel structure.

Original language	English
Pages (from-to)	3910-3913
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	18
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2008.06.033
State	Published - 2008.07.15

Keywords

DNA structure
Fluorescent probe
G-quadruplex
Stacking

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10.1016/j.bmcl.2008.06.033

Cite this

@article{468a227c61ee485cb58233461eb4e191,

title = "Detection of structure-switching in G-quadruplexes using end-stacking ability",

abstract = "G-quadruplex-forming ODNs containing nonpolar aromatic fluorophore moiety, APY at the dangling ends undergo π-stacking on surface of G-quadruplex, and the fluorescence change can be used to distinguish the structure-switching between the mixed parallel/antiparallel structure and antiparallel structure.",

keywords = "DNA structure, Fluorescent probe, G-quadruplex, Stacking",

author = "Seo, \{Young Jun\} and Lee, \{Il Joon\} and Kim, \{Byeang Hyean\}",

year = "2008",

month = jul,

day = "15",

doi = "10.1016/j.bmcl.2008.06.033",

language = "English",

volume = "18",

pages = "3910--3913",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

number = "14",

}

TY - JOUR

T1 - Detection of structure-switching in G-quadruplexes using end-stacking ability

AU - Seo, Young Jun

AU - Lee, Il Joon

AU - Kim, Byeang Hyean

PY - 2008/7/15

Y1 - 2008/7/15

N2 - G-quadruplex-forming ODNs containing nonpolar aromatic fluorophore moiety, APY at the dangling ends undergo π-stacking on surface of G-quadruplex, and the fluorescence change can be used to distinguish the structure-switching between the mixed parallel/antiparallel structure and antiparallel structure.

AB - G-quadruplex-forming ODNs containing nonpolar aromatic fluorophore moiety, APY at the dangling ends undergo π-stacking on surface of G-quadruplex, and the fluorescence change can be used to distinguish the structure-switching between the mixed parallel/antiparallel structure and antiparallel structure.

KW - DNA structure

KW - Fluorescent probe

KW - G-quadruplex

KW - Stacking

UR - https://www.scopus.com/pages/publications/47149106204

U2 - 10.1016/j.bmcl.2008.06.033

DO - 10.1016/j.bmcl.2008.06.033

M3 - Journal article

C2 - 18585032

AN - SCOPUS:47149106204

SN - 0960-894X

VL - 18

SP - 3910

EP - 3913

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 14

ER -

Detection of structure-switching in G-quadruplexes using end-stacking ability

Abstract

Keywords

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