Abstract
Korean Red Ginseng (KRG) is an herbal oriental medicine known to alleviate cardiovascular dysfunction. To analysis the expression of diabetic cardiac complication-associated genes in db/db mice, we studied the cardiac gene expression following KRG treatment. In result, a total of 585 genes were found to be changed in db/db mice. Among the changed expression, 245 genes were found to 2-fold upregulated, and 340 genes were 2-fold downregulated. In addition, the changed gene expressions were ameliorated by KRG. In conclusion, KRG may be possible to normalize cardiac gene expressions in db/db mice.
| Original language | English |
|---|---|
| Pages (from-to) | 450-455 |
| Number of pages | 6 |
| Journal | Journal of Ginseng Research |
| Volume | 45 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2021.05 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Diabetes mellitus
- Diabetic cardiac complication
- Gene profiling
- Microarray
- Panax ginseng
Quacquarelli Symonds(QS) Subject Topics
- Medicine
- Biological Sciences
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