Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci

Suk Ho Ban; Young Ran Kwon; Santosh Pandit; Young Soo Lee; Ho Keun Yi; Jae Gyu Jeon

doi:10.1016/j.fitote.2009.06.019

Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci

Suk Ho Ban
, Young Ran Kwon
, Santosh Pandit
, Young Soo Lee
, Ho Keun Yi
, Jae Gyu Jeon^*

^*Corresponding author for this work

Department of Dentistry

Institute of Oral Bioscience
Sun Moon University

Research output: Contribution to journal › Journal article › peer-review

38 Scopus citations

Abstract

Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Strptococcus mutans and Strptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities.

Original language	English
Pages (from-to)	30-34
Number of pages	5
Journal	Fitoterapia
Volume	81
Issue number	1
DOIs	https://doi.org/10.1016/j.fitote.2009.06.019
State	Published - 2010.01

Keywords

Glucosyltransferase
Glycolytic acid roduction
Polygonum cuspidatum
Strptococcus mutans
Strptococcus sobrinus

Access to Document

10.1016/j.fitote.2009.06.019

Cite this

@article{c165a9d59aba4f57a9e1a65ed06b535b,

title = "Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci",

abstract = "Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Strptococcus mutans and Strptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities.",

keywords = "Glucosyltransferase, Glycolytic acid roduction, Polygonum cuspidatum, Strptococcus mutans, Strptococcus sobrinus",

author = "Ban, \{Suk Ho\} and Kwon, \{Young Ran\} and Santosh Pandit and Lee, \{Young Soo\} and Yi, \{Ho Keun\} and Jeon, \{Jae Gyu\}",

year = "2010",

month = jan,

doi = "10.1016/j.fitote.2009.06.019",

language = "English",

volume = "81",

pages = "30--34",

journal = "Fitoterapia",

issn = "0367-326X",

number = "1",

}

TY - JOUR

T1 - Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci

AU - Ban, Suk Ho

AU - Kwon, Young Ran

AU - Pandit, Santosh

AU - Lee, Young Soo

AU - Yi, Ho Keun

AU - Jeon, Jae Gyu

PY - 2010/1

Y1 - 2010/1

N2 - Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Strptococcus mutans and Strptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities.

AB - Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Strptococcus mutans and Strptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities.

KW - Glucosyltransferase

KW - Glycolytic acid roduction

KW - Polygonum cuspidatum

KW - Strptococcus mutans

KW - Strptococcus sobrinus

UR - https://www.scopus.com/pages/publications/70449527578

U2 - 10.1016/j.fitote.2009.06.019

DO - 10.1016/j.fitote.2009.06.019

M3 - Journal article

C2 - 19616082

AN - SCOPUS:70449527578

SN - 0367-326X

VL - 81

SP - 30

EP - 34

JO - Fitoterapia

JF - Fitoterapia

IS - 1

ER -

Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this