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Effects of compounds isolated from the fruits of Rumex japonicus on the protein glycation

  • Dae Sik Jang
  • , Jong Min Kim
  • , Junghyun Kim
  • , Jeong Lim Yoo
  • , Young Sook Kim
  • , Jin Sook Kim*
  • *Corresponding author for this work
  • Korea Institute of Oriental Medicine

Research output: Contribution to journalJournal articlepeer-review

Abstract

An anthraquinone, emodin (1), and five flavonoids, kaempferol-3-O-β-D-glucoside (2), quercetin (3), quercitrin (4), isoquercitrin (5), and (+)-catechin (6), were isolated from an AcOEt-soluble extract of the fruits of Rumex japonicus. Their structures were determined by spectroscopic data interpretation. All the isolates were evaluated for their potential to inhibit AGEs (advanced glycation end products) formation and AGEs cross-linking, and to break already formed AGEs cross-links.

Original languageEnglish
Pages (from-to)2718-2723
Number of pages6
JournalChemistry and Biodiversity
Volume5
Issue number12
DOIs
StatePublished - 2008

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