Expression of neutralizing epitope of porcine epidemic diarrhea virus in potato plants

  • Young Sook Kim
  • , Tae Jin Kang
  • , Yong Suk Jang
  • , Moon Sik Yang*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

Abstract

Transgenic plants expressing recombinant proteins from pathogenic microorganisms provide an inexpensive edible vaccine for induction of local immunity. A neutralizing epitope of porcine epidemic diarrhea virus (PEDV) gene containing SEKDEL was expressed in potato using Agrobacterium-mediated transformation system. Putative transgenic plants were regenerated, and genomic PCR confirmed the presence of PEDV epitope gene in the potato plants. Based on the ELISA results, epitope of PEDV protein made up approximately 0.1% of the total soluble tuber protein.

Original languageEnglish
Pages (from-to)125-130
Number of pages6
JournalPlant Cell, Tissue and Organ Culture
Volume82
Issue number2
DOIs
StatePublished - 2005.08

Keywords

  • Neutralizing epitope
  • Plant expression
  • Porcine epidemic
  • Porcine epidemic diarrhea virus
  • Transgenic potato

Quacquarelli Symonds(QS) Subject Topics

  • Agriculture & Forestry

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