Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family

Hee Jeong Yoo; Ran Sook Woo; Soo Churl Cho; Boong Nyun Kim; Jae Won Kim; Min Sup Shin; Tae Won Park; Jung Woo Son; Un Sun Chung; Subin Park; Mira Park; Soon Ae Kim

doi:10.1016/j.psychres.2015.03.015

Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family

Hee Jeong Yoo
, Ran Sook Woo
, Soo Churl Cho
, Boong Nyun Kim
, Jae Won Kim
, Min Sup Shin
, Tae Won Park
, Jung Woo Son
, Un Sun Chung
, Subin Park
, Mira Park
, Soon Ae Kim^*

^*Corresponding author for this work

Department of Medicine

Research output: Contribution to journal › Journal article › peer-review

10 Scopus citations

Abstract

To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (. NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.

Original language	English
Pages (from-to)	366-368
Number of pages	3
Journal	Psychiatry Research
Volume	227
Issue number	2-3
DOIs	https://doi.org/10.1016/j.psychres.2015.03.015
State	Published - 2015.06.30

Keywords

Autism spectrum disorder
Family-based association study
Neuregulin 1

Quacquarelli Symonds(QS) Subject Topics

Medicine

Access to Document

10.1016/j.psychres.2015.03.015

Cite this

Yoo, H. J., Woo, R. S., Cho, S. C., Kim, B. N., Kim, J. W., Shin, M. S., Park, T. W., Son, J. W., Chung, U. S., Park, S., Park, M., & Kim, S. A. (2015). Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family. Psychiatry Research, 227(2-3), 366-368. https://doi.org/10.1016/j.psychres.2015.03.015

@article{41db8457e8174016adcd3bb5c33f75f4,

title = "Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family",

abstract = "To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (. NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.",

keywords = "Autism spectrum disorder, Family-based association study, Neuregulin 1",

author = "Yoo, \{Hee Jeong\} and Woo, \{Ran Sook\} and Cho, \{Soo Churl\} and Kim, \{Boong Nyun\} and Kim, \{Jae Won\} and Shin, \{Min Sup\} and Park, \{Tae Won\} and Son, \{Jung Woo\} and Chung, \{Un Sun\} and Subin Park and Mira Park and Kim, \{Soon Ae\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Ireland Ltd.",

year = "2015",

month = jun,

day = "30",

doi = "10.1016/j.psychres.2015.03.015",

language = "English",

volume = "227",

pages = "366--368",

journal = "Psychiatry Research",

issn = "0165-1781",

number = "2-3",

}

TY - JOUR

T1 - Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family

AU - Yoo, Hee Jeong

AU - Woo, Ran Sook

AU - Cho, Soo Churl

AU - Kim, Boong Nyun

AU - Kim, Jae Won

AU - Shin, Min Sup

AU - Park, Tae Won

AU - Son, Jung Woo

AU - Chung, Un Sun

AU - Park, Subin

AU - Park, Mira

AU - Kim, Soon Ae

PY - 2015/6/30

Y1 - 2015/6/30

N2 - To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (. NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.

AB - To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (. NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.

KW - Autism spectrum disorder

KW - Family-based association study

KW - Neuregulin 1

UR - https://www.scopus.com/pages/publications/84929131139

U2 - 10.1016/j.psychres.2015.03.015

DO - 10.1016/j.psychres.2015.03.015

M3 - Journal article

C2 - 25858800

AN - SCOPUS:84929131139

SN - 0165-1781

VL - 227

SP - 366

EP - 368

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2-3

ER -

Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

Access to Document

Other files and links

Fingerprint

Cite this