Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat

Bai Cheng Chen; Ajay Vijayakumar; Chul Park; Ulsoo Choi; Seung Yeol Nah; Jong Hoon Kim

doi:10.1016/j.jgr.2023.12.001

Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat

Bai Cheng Chen
, Ajay Vijayakumar
, Chul Park
, Ulsoo Choi
, Seung Yeol Nah^*
, Jong Hoon Kim^*

^*Corresponding author for this work

Department of Veterinary Medicine

Research output: Contribution to journal › Journal article › peer-review

4 Scopus citations

Abstract

The objective of the study is to estimate the potential of gintonin, as an immune enhancing agent through natural killer cell (NK cell) activity in cyclophosphamide (CY)-induced immunosuppressive animals. Accumulated results reveals that, gintonin attenuated CY-induced immunosuppression and it might modulate NK cell activity to boost the immunity.

Original language	English
Pages (from-to)	341-345
Number of pages	5
Journal	Journal of Ginseng Research
Volume	48
Issue number	3
DOIs	https://doi.org/10.1016/j.jgr.2023.12.001
State	Published - 2024.05

Keywords

Cyclophosphamide
Cytokines
Gintonin
Immune activity
NK receptors

Quacquarelli Symonds(QS) Subject Topics

Medicine
Biological Sciences

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10.1016/j.jgr.2023.12.001

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@article{a32c3f6d1be84a82b49c32b3819cdfbb,

title = "Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat",

abstract = "The objective of the study is to estimate the potential of gintonin, as an immune enhancing agent through natural killer cell (NK cell) activity in cyclophosphamide (CY)-induced immunosuppressive animals. Accumulated results reveals that, gintonin attenuated CY-induced immunosuppression and it might modulate NK cell activity to boost the immunity.",

keywords = "Cyclophosphamide, Cytokines, Gintonin, Immune activity, NK receptors",

author = "Chen, \{Bai Cheng\} and Ajay Vijayakumar and Chul Park and Ulsoo Choi and Nah, \{Seung Yeol\} and Kim, \{Jong Hoon\}",

note = "Publisher Copyright: {\textcopyright} 2024",

year = "2024",

month = may,

doi = "10.1016/j.jgr.2023.12.001",

language = "English",

volume = "48",

pages = "341--345",

journal = "Journal of Ginseng Research",

issn = "1226-8453",

number = "3",

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TY - JOUR

T1 - Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat

AU - Chen, Bai Cheng

AU - Vijayakumar, Ajay

AU - Park, Chul

AU - Choi, Ulsoo

AU - Nah, Seung Yeol

AU - Kim, Jong Hoon

PY - 2024/5

Y1 - 2024/5

N2 - The objective of the study is to estimate the potential of gintonin, as an immune enhancing agent through natural killer cell (NK cell) activity in cyclophosphamide (CY)-induced immunosuppressive animals. Accumulated results reveals that, gintonin attenuated CY-induced immunosuppression and it might modulate NK cell activity to boost the immunity.

AB - The objective of the study is to estimate the potential of gintonin, as an immune enhancing agent through natural killer cell (NK cell) activity in cyclophosphamide (CY)-induced immunosuppressive animals. Accumulated results reveals that, gintonin attenuated CY-induced immunosuppression and it might modulate NK cell activity to boost the immunity.

KW - Cyclophosphamide

KW - Cytokines

KW - Gintonin

KW - Immune activity

KW - NK receptors

UR - https://www.scopus.com/pages/publications/85180485099

U2 - 10.1016/j.jgr.2023.12.001

DO - 10.1016/j.jgr.2023.12.001

M3 - Journal article

AN - SCOPUS:85180485099

SN - 1226-8453

VL - 48

SP - 341

EP - 345

JO - Journal of Ginseng Research

JF - Journal of Ginseng Research

IS - 3

ER -

Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

Access to Document

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