Growth responses of Cassia obtusifolia toward human intestinal bacteria

  • Bo Kyung Sung
  • , Moo Key Kim
  • , Wang Hyu Lee
  • , Dong Heon Lee
  • , Hoi Seon Lee*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

Abstract

1,2-Dihydroxyanthraquinone (1) was isolated from the seed of Cassia obtusifolia through bioassay-guided fractionation. 1,2-Dihydroxyanthraquinone strongly inhibited the growth of Clostridium perfringens and Escherichia coli. Structure-activity relationship revealed that 1,4-dihydroxyanthraquinone (2) and 1,8-dihydroxyanthraquinone (3) had strong growth-inhibition against C. perfringens. In growth-promoting activity, 1,2-, 1,4-, and 1,8- dihydroxyanthraquinones exhibited strong growth-promoting activity to Bifidobacterium bifidum.

Original languageEnglish
Pages (from-to)505-509
Number of pages5
JournalFitoterapia
Volume75
Issue number5
DOIs
StatePublished - 2004.07

Keywords

  • 1,2-Dihydroxyanthraquinone
  • Anthraquinones
  • Cassia obtusifolia
  • Growth response
  • Intestinal bacteria

Quacquarelli Symonds(QS) Subject Topics

  • Pharmacy & Pharmacology

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