Handbook of intelligent scaffolds for tissue engineering and regenerative medicine

It has been recognized that tissue engineering and regenerative medicine offer an alternative technique to whole organ and tissue transplantation for diseased, failed, or malfunctioning organs. To reconstruct a new tissue by tissue engineering and regenerative medicine, triad components such as (1) cells that are harvested and dissociated from the donor tissue, (2) scaffold substrates as biomaterials in which cells are attached and cultured resulting in the implantation at the desired site of the functioning tissue, and (3) growth factors that are promoting and/or preventing cell adhesion, proliferation, migration, and differentiation by upregulating or downregulating the synthesis of protein, growth factors, and receptors are required. This book focuses on the intelligent scaffolds, associated biomaterials, and manufacturing in terms of tissue engineering and regenerative medicine, from basic principles to the most recent discoveries. The areas of focus include (1) ceramic and metal scaffold, (2) intelligent hydrogel, (3) electrospinning nanofiber, (3) novel biomaterials for scaffold, (4) novel fabrication methods for scaffold, and (5) scaffolds for target organ. The book comprises theoretical, experimental, preclinical, and clinical analysis of various properties of biomaterials, research methods and preparation techniques, and some promising applications.