Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle Cerebral Artery Occlusion

Chan Hyuk Lee; Sang Hak Yi; Byoung Soo Shin; Hyun Goo Kang

doi:10.3390/diagnostics12020398

Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle Cerebral Artery Occlusion

Chan Hyuk Lee
, Sang Hak Yi
, Byoung Soo Shin
, Hyun Goo Kang^*

^*Corresponding author for this work

Department of Medicine

Research output: Contribution to journal › Journal article › peer-review

Abstract

Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.

Original language	English
Article number	398
Journal	Diagnostics
Volume	12
Issue number	2
DOIs	https://doi.org/10.3390/diagnostics12020398
State	Published - 2022.02

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Atrial fibrillation
Cerebral emboli
Reperfusion injury

Quacquarelli Symonds(QS) Subject Topics

Biological Sciences

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10.3390/diagnostics12020398

Cite this

@article{c96b9b6d1d1043e28282e55c0df1d380,

title = "Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle Cerebral Artery Occlusion",

abstract = "Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.",

keywords = "Atrial fibrillation, Cerebral emboli, Reperfusion injury",

author = "Lee, \{Chan Hyuk\} and Yi, \{Sang Hak\} and Shin, \{Byoung Soo\} and Kang, \{Hyun Goo\}",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2022",

month = feb,

doi = "10.3390/diagnostics12020398",

language = "English",

volume = "12",

journal = "Diagnostics",

issn = "2075-4418",

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T1 - Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle Cerebral Artery Occlusion

AU - Lee, Chan Hyuk

AU - Yi, Sang Hak

AU - Shin, Byoung Soo

AU - Kang, Hyun Goo

PY - 2022/2

Y1 - 2022/2

N2 - Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.

AB - Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.

KW - Atrial fibrillation

KW - Cerebral emboli

KW - Reperfusion injury

UR - https://www.scopus.com/pages/publications/85124072339

U2 - 10.3390/diagnostics12020398

DO - 10.3390/diagnostics12020398

M3 - Journal article

AN - SCOPUS:85124072339

SN - 2075-4418

VL - 12

JO - Diagnostics

JF - Diagnostics

IS - 2

M1 - 398

ER -

Hemorrhagic Transformation after Intravenous Tissue Plasminogen Activator Administration in Acute Distal Middle Cerebral Artery Occlusion

Abstract

UN SDGs

Keywords

Quacquarelli Symonds(QS) Subject Topics

Access to Document

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