Abstract
We delineate the excellent bactericidal efficacy of stable heterojunction nanocomposites composed of single-walled carbon nanotubes (SWCNTs) and copper(II) oxide (CuO) synthesized via facile recrystallization and calcination. The bactericidal effectiveness of the fabricated nanocomposites was examined using the standard broth-dilution method and the growth-inhibition-zone analysis method, in which bacteria cultured in an incubator in tryptic soy broth medium were subjected to the prepared samples. The bactericidal activity of all of the as-synthesized samples is evident in both methods, displaying a substantial decrease in bacterial colonies and resulting in clear inhibition zones, respectively. Among the CuO–SWCNT nanocomposites, the sample subjected to calcination at 500 °C for 5 h was found to exhibit the best performance against Staphylococcus aureus and Escherichia coli, forming inhibition zones 182% and 162% larger than those formed by pure CuO, respectively.
| Original language | English |
|---|---|
| Article number | 119937 |
| Journal | International Journal of Pharmaceutics |
| Volume | 590 |
| DOIs | |
| State | Published - 2020.11.30 |
Keywords
- Antibacterial
- Bactericidal
- CuO-SWCNT nanostructures
- Escherichia coli
- Growth inhibition
- Heterojunction
- Staphylococcus aureus
Quacquarelli Symonds(QS) Subject Topics
- Pharmacy & Pharmacology
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