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Heterojunction formation between copper(II) oxide nanoparticles and single-walled carbon nanotubes to enhance antibacterial performance

  • Kamal Prasad Sapkota
  • , Md Mehedi Hassan
  • , Sita Shrestha
  • , Md Abu Hanif
  • , Md Akherul Islam
  • , Jeasmin Akter
  • , Hafiz Ghulam Abbas
  • , Jae Ryang Hahn*
  • *Corresponding author for this work
  • Jeonbuk National University
  • Tribhuvan University

Research output: Contribution to journalJournal articlepeer-review

Abstract

We delineate the excellent bactericidal efficacy of stable heterojunction nanocomposites composed of single-walled carbon nanotubes (SWCNTs) and copper(II) oxide (CuO) synthesized via facile recrystallization and calcination. The bactericidal effectiveness of the fabricated nanocomposites was examined using the standard broth-dilution method and the growth-inhibition-zone analysis method, in which bacteria cultured in an incubator in tryptic soy broth medium were subjected to the prepared samples. The bactericidal activity of all of the as-synthesized samples is evident in both methods, displaying a substantial decrease in bacterial colonies and resulting in clear inhibition zones, respectively. Among the CuO–SWCNT nanocomposites, the sample subjected to calcination at 500 °C for 5 h was found to exhibit the best performance against Staphylococcus aureus and Escherichia coli, forming inhibition zones 182% and 162% larger than those formed by pure CuO, respectively.

Original languageEnglish
Article number119937
JournalInternational Journal of Pharmaceutics
Volume590
DOIs
StatePublished - 2020.11.30

Keywords

  • Antibacterial
  • Bactericidal
  • CuO-SWCNT nanostructures
  • Escherichia coli
  • Growth inhibition
  • Heterojunction
  • Staphylococcus aureus

Quacquarelli Symonds(QS) Subject Topics

  • Pharmacy & Pharmacology

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