Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity

In Kyoung Lee; Bong Sik Yun

doi:10.1016/j.bmcl.2006.01.121

Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity

In Kyoung Lee
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Korea Research Institute of Bioscience and Biotechnology

Research output: Contribution to journal › Journal article › peer-review

69 Scopus citations

Abstract

Three new free radical scavengers were isolated from the methanolic extract of the fruiting bodies of Inonotus xeranticus (Hymenochaetaceae), along with the known compound davallialactone. Their structures were established as hispidin analogs by extensive NMR spectral data. Compounds 3 and 4 displayed significant scavenging activity against the superoxide radical anion, ABTS radical cation, and DPPH radical, while1 and 2 exhibited potent antioxidative activity only against ABTS radical cation.

Original language	English
Pages (from-to)	2376-2379
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	16
Issue number	9
DOIs	https://doi.org/10.1016/j.bmcl.2006.01.121
State	Published - 2006.05.1

Keywords

Antioxidant
Free radical scavenger
Hispidin analog
Inonotus xeranticus
Mushroom

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10.1016/j.bmcl.2006.01.121

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title = "Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity",

abstract = "Three new free radical scavengers were isolated from the methanolic extract of the fruiting bodies of Inonotus xeranticus (Hymenochaetaceae), along with the known compound davallialactone. Their structures were established as hispidin analogs by extensive NMR spectral data. Compounds 3 and 4 displayed significant scavenging activity against the superoxide radical anion, ABTS radical cation, and DPPH radical, while1 and 2 exhibited potent antioxidative activity only against ABTS radical cation.",

keywords = "Antioxidant, Free radical scavenger, Hispidin analog, Inonotus xeranticus, Mushroom",

author = "Lee, \{In Kyoung\} and Yun, \{Bong Sik\}",

year = "2006",

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doi = "10.1016/j.bmcl.2006.01.121",

language = "English",

volume = "16",

pages = "2376--2379",

journal = "Bioorganic and Medicinal Chemistry Letters",

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T1 - Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity

AU - Lee, In Kyoung

AU - Yun, Bong Sik

PY - 2006/5/1

Y1 - 2006/5/1

N2 - Three new free radical scavengers were isolated from the methanolic extract of the fruiting bodies of Inonotus xeranticus (Hymenochaetaceae), along with the known compound davallialactone. Their structures were established as hispidin analogs by extensive NMR spectral data. Compounds 3 and 4 displayed significant scavenging activity against the superoxide radical anion, ABTS radical cation, and DPPH radical, while1 and 2 exhibited potent antioxidative activity only against ABTS radical cation.

AB - Three new free radical scavengers were isolated from the methanolic extract of the fruiting bodies of Inonotus xeranticus (Hymenochaetaceae), along with the known compound davallialactone. Their structures were established as hispidin analogs by extensive NMR spectral data. Compounds 3 and 4 displayed significant scavenging activity against the superoxide radical anion, ABTS radical cation, and DPPH radical, while1 and 2 exhibited potent antioxidative activity only against ABTS radical cation.

KW - Antioxidant

KW - Free radical scavenger

KW - Hispidin analog

KW - Inonotus xeranticus

KW - Mushroom

UR - https://www.scopus.com/pages/publications/33644976739

U2 - 10.1016/j.bmcl.2006.01.121

DO - 10.1016/j.bmcl.2006.01.121

M3 - Journal article

C2 - 16488146

AN - SCOPUS:33644976739

SN - 0960-894X

VL - 16

SP - 2376

EP - 2379

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 9

ER -

Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity

Abstract

Keywords

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