Igloo-stock pattering for domain separation of surface on microparticle by dehydration and rehydration process

In previous research, encoded microparticles have been developed to authenticate products, providing features such as small volume and invisibility. The encoded microparticles can be used in a variety of fields such as, anti-counterfeiting, pharmaceutical identification and traceability, food traceability and product identification. Conventional microparticles are fabricated by mixing optically functional materials such as, fluorescent nanoparticles, colored dye, and transparent nanospheres. [1, 2] Unfortunately, multimaterial fabrications, including those with fluorescent materials, have a few limitations for bio-applications due to their toxicity and incompatibility with biological systems.