Impact of electrospun biomimetic extracellular environment on proliferation and intercellular communication of muscle precursor cells: An overview - intercellular communication of muscle precursor cells with extracellular environment

Nanotextured materials or nanomaterials offer diverse remarkable applications in various walks of life owing to their unique geometry. This chapter is focused on the synthesis and characterization of electrospun nanofibrous matrices as a novel biomimetic scaffold for the cultivation of cells and tissues; in particular muscle cells and tissues. Tissue engineering is exceedingly interdisciplinary branch of science which integrates the benefits of life sciences and medicine with those of engineering. In order to cultivate muscle cells in-vitro, it is necessary to have a 3D scaffold. In tissue engineering applications or even in 3D cell cultures, the biological cross talk between cells and the scaffold is controlled by the material properties and scaffold characteristics. This chapter provides a general overview of the common approaches and techniques used for designing nanofibrous scaffolds for culture of cells specifically muscle cells. The limitations and benefits of the tissue engineering are discussed.