Interactions of proteins and cells on functional group gradient surfaces

Charge gradient and comb-like polyethylene oxide (PEO) gradient surfaces were prepared on low density polyethylene (PE) sheets by corona discharge treatment with gradually increasing power and the following graft copolymerization of chargeable functional group- and PEO-containing vinyl monomers, respectively. Those gradient surfaces were used to investigate protein or cell interactions in relation to the surface functional groups and their density of polymeric materials.