Korean Red Ginseng modulates immune function by upregulating CD4+CD8+ T cells and NK cell activities on porcine

Md Jahangir Alam; Mohammad Amjad Hossain; Kiran D. Bhilare; Chang Won Kang; Jong Hoon Kim

doi:10.1016/j.jgr.2022.10.002

Korean Red Ginseng modulates immune function by upregulating CD4⁺CD8⁺ T cells and NK cell activities on porcine

Md Jahangir Alam
, Mohammad Amjad Hossain
, Kiran D. Bhilare
, Chang Won Kang
, Jong Hoon Kim^*

^*Corresponding author for this work

Department of Veterinary Medicine

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

6 Scopus citations

Abstract

In the present study, we investigated whether treatment with KRG improve the parameters of immune activity such as the cytotoxicity, populations of CD4⁺ CD8⁺T cell, CD3⁻CD172⁻CD8⁺ NK cell and CD172⁺ monocyte as well as natural cytotoxicity receptors such as Nkp46, Nkp44, Nkp30. In results, KRG significantly increased these immune activities. These results indicate that KRG has distinct immune-enhancing effects by increasing the roles of T cells and NK cell in porcine.

Original language	English
Pages (from-to)	155-158
Number of pages	4
Journal	Journal of Ginseng Research
Volume	47
Issue number	1
DOIs	https://doi.org/10.1016/j.jgr.2022.10.002
State	Published - 2023.01

Keywords

CD4 CD8T cell
cytotoxic receptors
immune activity
Korean Red Ginseng

Quacquarelli Symonds(QS) Subject Topics

Medicine
Biological Sciences

Access to Document

10.1016/j.jgr.2022.10.002

Cite this

@article{37e2e8bcc8c64202a2d8636f802cc03c,

title = "Korean Red Ginseng modulates immune function by upregulating CD4+CD8+ T cells and NK cell activities on porcine",

abstract = "In the present study, we investigated whether treatment with KRG improve the parameters of immune activity such as the cytotoxicity, populations of CD4+ CD8+T cell, CD3−CD172−CD8+ NK cell and CD172+ monocyte as well as natural cytotoxicity receptors such as Nkp46, Nkp44, Nkp30. In results, KRG significantly increased these immune activities. These results indicate that KRG has distinct immune-enhancing effects by increasing the roles of T cells and NK cell in porcine.",

keywords = "CD4 CD8T cell, cytotoxic receptors, immune activity, Korean Red Ginseng",

author = "Alam, \{Md Jahangir\} and Hossain, \{Mohammad Amjad\} and Bhilare, \{Kiran D.\} and Kang, \{Chang Won\} and Kim, \{Jong Hoon\}",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2023",

month = jan,

doi = "10.1016/j.jgr.2022.10.002",

language = "English",

volume = "47",

pages = "155--158",

journal = "Journal of Ginseng Research",

issn = "1226-8453",

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TY - JOUR

T1 - Korean Red Ginseng modulates immune function by upregulating CD4+CD8+ T cells and NK cell activities on porcine

AU - Alam, Md Jahangir

AU - Hossain, Mohammad Amjad

AU - Bhilare, Kiran D.

AU - Kang, Chang Won

AU - Kim, Jong Hoon

PY - 2023/1

Y1 - 2023/1

N2 - In the present study, we investigated whether treatment with KRG improve the parameters of immune activity such as the cytotoxicity, populations of CD4+ CD8+T cell, CD3−CD172−CD8+ NK cell and CD172+ monocyte as well as natural cytotoxicity receptors such as Nkp46, Nkp44, Nkp30. In results, KRG significantly increased these immune activities. These results indicate that KRG has distinct immune-enhancing effects by increasing the roles of T cells and NK cell in porcine.

AB - In the present study, we investigated whether treatment with KRG improve the parameters of immune activity such as the cytotoxicity, populations of CD4+ CD8+T cell, CD3−CD172−CD8+ NK cell and CD172+ monocyte as well as natural cytotoxicity receptors such as Nkp46, Nkp44, Nkp30. In results, KRG significantly increased these immune activities. These results indicate that KRG has distinct immune-enhancing effects by increasing the roles of T cells and NK cell in porcine.

KW - CD4 CD8T cell

KW - cytotoxic receptors

KW - immune activity

KW - Korean Red Ginseng

UR - https://www.scopus.com/pages/publications/85140233643

U2 - 10.1016/j.jgr.2022.10.002

DO - 10.1016/j.jgr.2022.10.002

M3 - Journal article

AN - SCOPUS:85140233643

SN - 1226-8453

VL - 47

SP - 155

EP - 158

JO - Journal of Ginseng Research

JF - Journal of Ginseng Research

IS - 1

ER -