Skip to main navigation Skip to search Skip to main content

Lactiplantibacillus plantarum L67 probiotics vs paraprobiotics for reducing pro-inflammatory responses in colitis mice

  • Sooyeon Song
  • , Anna Jeong
  • , Jina Lim
  • , Bum Keun Kim
  • , Dong June Park
  • , Sejong Oh*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

Abstract

Probiotics improve intestinal symptoms and reduce damage in patients with inflammatory bowel disease (IBD). However, live bacteria are not consistently effective for IBD patients because of their weaker immune system and damaged intestinal epithelial cells. This study compared the suppression effect of probiotic (L67) and paraprobiotic Lactiplantibacillus plantarum L67 (PPL67) cells on dextran sulphate sodium (DSS)-treated Institute of Cancer Research mice. The results showed that the administration of PPL67 to DSS-treated mice mitigated the symptoms of colitis as evidenced by reductions in DAI define levels and the pro-inflammatory factors. So, these results indicate that L. plantarum L67 may prevent the pathogenesis of chronic colitis in a safer and more stable way.

Original languageEnglish
Pages (from-to)168-177
Number of pages10
JournalInternational Journal of Dairy Technology
Volume76
Issue number1
DOIs
StatePublished - 2023.02

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Colitis
  • Dextran sulphate sodium
  • Heat-inactivated
  • Lactiplantibacillus plantarum L67
  • Paraprobiotics

Quacquarelli Symonds(QS) Subject Topics

  • Agriculture & Forestry
  • Engineering - Petroleum
  • Engineering - Chemical

Fingerprint

Dive into the research topics of 'Lactiplantibacillus plantarum L67 probiotics vs paraprobiotics for reducing pro-inflammatory responses in colitis mice'. Together they form a unique fingerprint.

Cite this