Leukocyte markers differentiate non-infected from spontaneously infected dairy cows

  • Do Hyeon Yu
  • , Jong Hyeon Lee
  • , Ru Hui Song
  • , Dong Ho Noh
  • , Ying Hua Li
  • , Mi Jin Lee
  • , Jin Ho Park*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

Abstract

Spontaneously infected and non-infected dairy cows were assessed in a cross-sectional study aimed at determining whether bovine leukocyte markers may diagnose intra-mammary infections (bovine mastitis). Animals located in herds where bovine mastitis was highly prevalent were investigated (n = 31 animals). The expression of three cell-surface markers (CD11b, CD4 and CD8) was assessed, and the somatic cell count (SCC) and bacteriological analyses (both cultures and PCR tests) were also conducted. Cows identified as infected revealed statistically significant higher milk leukocyte CD11b, CD4 percentage and milk CD4/CD8 ratios than non-infected cows. Immunological markers may diagnose spontaneous bovine mastitis.

Original languageEnglish
Pages (from-to)524-527
Number of pages4
JournalJournal of Veterinary Clinics
Volume26
Issue number6
StatePublished - 2009

Keywords

  • Bovine mastitis
  • CD11B/CD4/CD8
  • Flow cytometry

Quacquarelli Symonds(QS) Subject Topics

  • Veterinary Science

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