TY - CHAP
T1 - Luminescent Nanomaterials (II)
AU - Chang, Hyejin
AU - Kim, Jaehi
AU - Lee, Sang Hun
AU - Rho, Won Yeop
AU - Lee, Jong Hun
AU - Jeong, Dae Hong
AU - Jun, Bong Hyun
N1 - Publisher Copyright:
© 2021, Springer Nature Singapore Pte Ltd.
PY - 2021
Y1 - 2021
N2 - In this review, we focus on sensing techniques and biological applications of various luminescent nanoparticles including quantum dot (QD), up-conversion nanoparticles (UCNPs) following the previous chapter. Fluorescent phenomena can be regulated or shifted by interaction between biological targets and luminescence probes depending on their distance, which is so-called Fӧrster resonance energy transfer (FRET). QD-based FRET technique, which has been widely applied as a bioanalytical tool, is described. We discuss time-resolved fluorescence (TRF) imaging and flow cytometry technique, using photoluminescent nanoparticles with unique properties for effectively improving selectivity and sensitivity. Based on these techniques, bioanalytical and biomedical application, bioimaging with QD, UCNPs, and Euripium-activated luminescent nanoprobes are covered. Combination of optical property of these luminescent nanoparticles with special functions such as drug delivery, photothermal therapy (PTT), and photodynamic therapy (PDT) is also described.
AB - In this review, we focus on sensing techniques and biological applications of various luminescent nanoparticles including quantum dot (QD), up-conversion nanoparticles (UCNPs) following the previous chapter. Fluorescent phenomena can be regulated or shifted by interaction between biological targets and luminescence probes depending on their distance, which is so-called Fӧrster resonance energy transfer (FRET). QD-based FRET technique, which has been widely applied as a bioanalytical tool, is described. We discuss time-resolved fluorescence (TRF) imaging and flow cytometry technique, using photoluminescent nanoparticles with unique properties for effectively improving selectivity and sensitivity. Based on these techniques, bioanalytical and biomedical application, bioimaging with QD, UCNPs, and Euripium-activated luminescent nanoprobes are covered. Combination of optical property of these luminescent nanoparticles with special functions such as drug delivery, photothermal therapy (PTT), and photodynamic therapy (PDT) is also described.
KW - Drug delivery
KW - Fӧrster resonance energy transfer (FRET)
KW - Photodynamic therapy (PDT)
KW - Photothermal therapy (PTT)
KW - Quantum dot (QD)
KW - Time-resolved fluorescence (TRF)
KW - Up-conversion nanoparticles (UCNPs)
UR - https://www.scopus.com/pages/publications/85103538663
U2 - 10.1007/978-981-33-6158-4_5
DO - 10.1007/978-981-33-6158-4_5
M3 - Chapter
C2 - 33782870
AN - SCOPUS:85103538663
T3 - Advances in Experimental Medicine and Biology
SP - 97
EP - 132
BT - Advances in Experimental Medicine and Biology
PB - Springer
ER -