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Mitochondria in relation to cancer metastasis

  • Bidur Bhandary
  • , Anu Marahatta
  • , Hyung Ryong Kim
  • , Han Jung Chae*
  • *Corresponding author for this work
  • Jeonbuk National University
  • Wonkwang University

Research output: Contribution to journalReview articlepeer-review

Abstract

Mitochondria, also known as "Power House of cell," are crucial organelles, regulating energy metabolism. Recently, an involvement of mitochondria in cancer occurrence and metastasis has been proposed. The roles of mitochondria in cancer progression/metastasis include alteration of glycolysis, regulation of ROS and suppression of intrinsic apoptosis. This mini-review explains the specific mitochondrial characteristics during cancer metastasis with past and recent findings. It may contribute to understanding mitochondria-related mechanisms of cancer metastasis.

Original languageEnglish
Pages (from-to)623-627
Number of pages5
JournalJournal of Bioenergetics and Biomembranes
Volume44
Issue number6
DOIs
StatePublished - 2012.12

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Apoptosis
  • Cancer metastasis
  • Glycolysis
  • Mitochondria
  • ROS

Quacquarelli Symonds(QS) Subject Topics

  • Anatomy & Physiology
  • Biological Sciences

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