ncRDense: A novel computational approach for classification of non-coding RNA family by deep learning

  • Tuvshinbayar Chantsalnyam
  • , Arslan Siraj
  • , Hilal Tayara*
  • , Kil To Chong*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

Abstract

With the rapidly growing importance of biological research, non-coding RNAs (ncRNA) attract more attention in biology and bioinformatics. They play vital roles in biological processes such as transcription and translation. Classification of ncRNAs is essential to our understanding of disease mechanisms and treatment design. Many approaches to ncRNA classification have been developed, several of which use machine learning and deep learning. In this paper, we construct a novel deep learning-based architecture, ncRDense, to effectively classify and distinguish ncRNA families. In a comparative study, our model produces comparable results with existing state-of-the-art methods. Finally, we built a freely accessible web server for the ncRDense tool, which is available at http://nsclbio.jbnu.ac.kr/tools/ncRDense/.

Original languageEnglish
Pages (from-to)3030-3038
Number of pages9
JournalGenomics
Volume113
Issue number5
DOIs
StatePublished - 2021.09

Keywords

  • Classification
  • Deep learning
  • Densenet
  • Feature encoding
  • Non-coding RNA

Quacquarelli Symonds(QS) Subject Topics

  • Biological Sciences

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