New antioxidants from the culture broth of Coprinopsis echinospora

Dae Won Ki; Dae Won Kim; Ja Gyeong Song; E. Eum Woo; Dae Cheol Choi; In Kyoung Lee; Bong Sik Yun

doi:10.1038/s41429-021-00495-2

New antioxidants from the culture broth of Coprinopsis echinospora

Dae Won Ki
, Dae Won Kim
, Ja Gyeong Song
, E. Eum Woo
, Dae Cheol Choi
, In Kyoung Lee
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

3 Scopus citations

Abstract

During the search for natural antioxidants from fungal metabolites, three new sesquiterpene derivatives (1-3) have been isolated from the culture broth of Coprinopsis echinospora. Their structures were determined by spectroscopic methods, mainly NMR and mass spectrometric analyses. These compounds exhibited antioxidant activity with IC₅₀ values in the range of 34.4–144.5 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.

Original language	English
Pages (from-to)	113-116
Number of pages	4
Journal	Journal of Antibiotics
Volume	75
Issue number	2
DOIs	https://doi.org/10.1038/s41429-021-00495-2
State	Published - 2022.02

Quacquarelli Symonds(QS) Subject Topics

Pharmacy & Pharmacology

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10.1038/s41429-021-00495-2

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title = "New antioxidants from the culture broth of Coprinopsis echinospora",

abstract = "During the search for natural antioxidants from fungal metabolites, three new sesquiterpene derivatives (1-3) have been isolated from the culture broth of Coprinopsis echinospora. Their structures were determined by spectroscopic methods, mainly NMR and mass spectrometric analyses. These compounds exhibited antioxidant activity with IC50 values in the range of 34.4–144.5 μM in the 2,2{\textquoteright}-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.",

author = "Ki, \{Dae Won\} and Kim, \{Dae Won\} and Song, \{Ja Gyeong\} and Woo, \{E. Eum\} and Choi, \{Dae Cheol\} and Lee, \{In Kyoung\} and Yun, \{Bong Sik\}",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to the Japan Antibiotics Research Association.",

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doi = "10.1038/s41429-021-00495-2",

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T1 - New antioxidants from the culture broth of Coprinopsis echinospora

AU - Ki, Dae Won

AU - Kim, Dae Won

AU - Song, Ja Gyeong

AU - Woo, E. Eum

AU - Choi, Dae Cheol

AU - Lee, In Kyoung

AU - Yun, Bong Sik

PY - 2022/2

Y1 - 2022/2

N2 - During the search for natural antioxidants from fungal metabolites, three new sesquiterpene derivatives (1-3) have been isolated from the culture broth of Coprinopsis echinospora. Their structures were determined by spectroscopic methods, mainly NMR and mass spectrometric analyses. These compounds exhibited antioxidant activity with IC50 values in the range of 34.4–144.5 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.

AB - During the search for natural antioxidants from fungal metabolites, three new sesquiterpene derivatives (1-3) have been isolated from the culture broth of Coprinopsis echinospora. Their structures were determined by spectroscopic methods, mainly NMR and mass spectrometric analyses. These compounds exhibited antioxidant activity with IC50 values in the range of 34.4–144.5 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.

UR - https://www.scopus.com/pages/publications/85121044879

U2 - 10.1038/s41429-021-00495-2

DO - 10.1038/s41429-021-00495-2

M3 - Journal article

C2 - 34903860

AN - SCOPUS:85121044879

SN - 0021-8820

VL - 75

SP - 113

EP - 116

JO - Journal of Antibiotics

JF - Journal of Antibiotics

IS - 2

ER -

New antioxidants from the culture broth of Coprinopsis echinospora

Abstract

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