New antioxidants from the culture broth of Hericium coralloides

Ji Yul Kim; E. Eum Woo; In Kyoung Lee; Bong Sik Yun

doi:10.1038/s41429-018-0067-6

New antioxidants from the culture broth of Hericium coralloides

Ji Yul Kim
, E. Eum Woo
, In Kyoung Lee
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

22 Scopus citations

Abstract

In our effort to find antioxidants from the higher fungi, we isolated three new compounds (1–3) with a known compound, spirobenzofuran (4), from the culture broth of Hericium coralloides. Bioassay-guided fractionation led to the isolation of these compounds, and we determined the chemical structures through spectroscopic methods. These compounds exhibited antioxidant activity in the range of IC ₅₀ values of 29-66 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.

Original language	English
Pages (from-to)	822-825
Number of pages	4
Journal	Journal of Antibiotics
Volume	71
Issue number	9
DOIs	https://doi.org/10.1038/s41429-018-0067-6
State	Published - 2018.09.1

Quacquarelli Symonds(QS) Subject Topics

Pharmacy & Pharmacology

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10.1038/s41429-018-0067-6

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@article{69f11f07880144479204655013dae8cc,

title = "New antioxidants from the culture broth of Hericium coralloides",

abstract = " In our effort to find antioxidants from the higher fungi, we isolated three new compounds (1–3) with a known compound, spirobenzofuran (4), from the culture broth of Hericium coralloides. Bioassay-guided fractionation led to the isolation of these compounds, and we determined the chemical structures through spectroscopic methods. These compounds exhibited antioxidant activity in the range of IC 50 values of 29-66 μM in the 2,2{\textquoteright}-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.",

author = "Kim, \{Ji Yul\} and Woo, \{E. Eum\} and Lee, \{In Kyoung\} and Yun, \{Bong Sik\}",

note = "Publisher Copyright: {\textcopyright} 2018, The Author(s) under exclusive licence to the Japan Antibiotics Research Association.",

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doi = "10.1038/s41429-018-0067-6",

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T1 - New antioxidants from the culture broth of Hericium coralloides

AU - Kim, Ji Yul

AU - Woo, E. Eum

AU - Lee, In Kyoung

AU - Yun, Bong Sik

PY - 2018/9/1

Y1 - 2018/9/1

N2 - In our effort to find antioxidants from the higher fungi, we isolated three new compounds (1–3) with a known compound, spirobenzofuran (4), from the culture broth of Hericium coralloides. Bioassay-guided fractionation led to the isolation of these compounds, and we determined the chemical structures through spectroscopic methods. These compounds exhibited antioxidant activity in the range of IC 50 values of 29-66 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.

AB - In our effort to find antioxidants from the higher fungi, we isolated three new compounds (1–3) with a known compound, spirobenzofuran (4), from the culture broth of Hericium coralloides. Bioassay-guided fractionation led to the isolation of these compounds, and we determined the chemical structures through spectroscopic methods. These compounds exhibited antioxidant activity in the range of IC 50 values of 29-66 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.

UR - https://www.scopus.com/pages/publications/85047122293

U2 - 10.1038/s41429-018-0067-6

DO - 10.1038/s41429-018-0067-6

M3 - Journal article

C2 - 29773898

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SN - 0021-8820

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SP - 822

EP - 825

JO - Journal of Antibiotics

JF - Journal of Antibiotics

IS - 9

ER -

New antioxidants from the culture broth of Hericium coralloides

Abstract

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