New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction

In Kyoung Lee; Yun Woo Jang; Seung Hun Yu; Bong Sik Yun

doi:10.1016/j.bmcl.2007.06.034

New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction

In Kyoung Lee
, Yun Woo Jang
, Seung Hun Yu
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Korea Research Institute of Bioscience and Biotechnology
Chungnam National University

Research output: Contribution to journal › Journal article › peer-review

8 Scopus citations

Abstract

New triterpene glucosides, oligoporins A (1), B (2), and C (3), were isolated from the methanolic extract of the fruiting bodies of Oligoporus tephroleucus (Polyporaceae). Their structures were established by spectroscopic methods. These compounds significantly exhibited protective effect to plasmid DNA damage by hydroxyl radical (^·OH) generated from the Fenton reaction with hydrogen peroxide and ferrous.

Original language	English
Pages (from-to)	4906-4909
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	17
Issue number	17
DOIs	https://doi.org/10.1016/j.bmcl.2007.06.034
State	Published - 2007.09.1

Keywords

DNA protection
Fenton reaction
Oligoporins
Oligoporus tephroleucus

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10.1016/j.bmcl.2007.06.034

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@article{3f6a7a08cf6b4646852eacfdd07a9a1c,

title = "New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction",

abstract = "New triterpene glucosides, oligoporins A (1), B (2), and C (3), were isolated from the methanolic extract of the fruiting bodies of Oligoporus tephroleucus (Polyporaceae). Their structures were established by spectroscopic methods. These compounds significantly exhibited protective effect to plasmid DNA damage by hydroxyl radical (·OH) generated from the Fenton reaction with hydrogen peroxide and ferrous.",

keywords = "DNA protection, Fenton reaction, Oligoporins, Oligoporus tephroleucus",

author = "Lee, \{In Kyoung\} and Jang, \{Yun Woo\} and Yu, \{Seung Hun\} and Yun, \{Bong Sik\}",

year = "2007",

month = sep,

day = "1",

doi = "10.1016/j.bmcl.2007.06.034",

language = "English",

volume = "17",

pages = "4906--4909",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

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TY - JOUR

T1 - New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction

AU - Lee, In Kyoung

AU - Jang, Yun Woo

AU - Yu, Seung Hun

AU - Yun, Bong Sik

PY - 2007/9/1

Y1 - 2007/9/1

N2 - New triterpene glucosides, oligoporins A (1), B (2), and C (3), were isolated from the methanolic extract of the fruiting bodies of Oligoporus tephroleucus (Polyporaceae). Their structures were established by spectroscopic methods. These compounds significantly exhibited protective effect to plasmid DNA damage by hydroxyl radical (·OH) generated from the Fenton reaction with hydrogen peroxide and ferrous.

AB - New triterpene glucosides, oligoporins A (1), B (2), and C (3), were isolated from the methanolic extract of the fruiting bodies of Oligoporus tephroleucus (Polyporaceae). Their structures were established by spectroscopic methods. These compounds significantly exhibited protective effect to plasmid DNA damage by hydroxyl radical (·OH) generated from the Fenton reaction with hydrogen peroxide and ferrous.

KW - DNA protection

KW - Fenton reaction

KW - Oligoporins

KW - Oligoporus tephroleucus

UR - https://www.scopus.com/pages/publications/34547507900

U2 - 10.1016/j.bmcl.2007.06.034

DO - 10.1016/j.bmcl.2007.06.034

M3 - Journal article

C2 - 17588752

AN - SCOPUS:34547507900

SN - 0960-894X

VL - 17

SP - 4906

EP - 4909

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 17

ER -

New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction

Abstract

Keywords

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