Abstract
A series of pyrazoloxyphenyl benzoyl urea derivatives was designed and synthesized for cytotoxic evaluation as potential antitumor agents. The synthetic compounds were evaluated for in vitro cytotoxicity against five human tumor cell lines, including A-549, SKOV-3, SK-MEL-2, XF-498 and HCT-15. Among others, compound 11 exhibited 50∼100 times greater antitumor activities than the commercial product, Cisplatin.
| Original language | English |
|---|---|
| Pages (from-to) | 781-785 |
| Number of pages | 5 |
| Journal | Archives of Pharmacal Research |
| Volume | 25 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2002.12 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Anticancer
- Benzoyl Urea
- Cisplatin
- Cytotoxicity
Quacquarelli Symonds(QS) Subject Topics
- Medicine
- Engineering - Petroleum
- Pharmacy & Pharmacology
- Chemistry
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