One-pot hydrothermal synthesis of CuS/CoS composite for electrochemical non-enzymatic glucose sensor

Herein, a CuS/CoS electrode material was synthesized using a one-step hydrothermal method as an efficient electrocatalyst for a non-enzymatic glucose sensor. The nanocomposites were characterized by Field emission scanning electron microscope (FE-SEM), Transmission electron microscope (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The CuS/CoS composite loaded glassy carbon electrode was used to investigate electrochemical properties using cyclic voltammetry (CV) and chronoamperometry (CA). The results showed 314.85 μA mM⁻¹ cm⁻² sensitivity and 1.71 μM detection limit. Selectivity of the sensor was examined over potential interfering species that exhibits the distinct increased current response on addition of glucose before and after addition of interfering species evident the selectivity of CuS/CoS electrode material. Moreover, the CuS/CoS composite-based non-enzymatic glucose sensor revealed considerable stability, selectivity over interfering species, and viability for glucose determination in diluted human serum samples, which provide efficient and cost-effective strategy to develop non-enzymatic electrochemical glucose sensing platform.