Abstract
Duck feet collagen (DC) has recently been used as a stable and safe source for tissue engineering. In this study, we have prepared a series of collagen scaffolds by mixing poly(lactic-co-glycolide)(PLGA) solutions with different percentages of collagen extracted from duck feet. Bone marow mesenchymal stem cells (BMSC) were cultured on the prepared DC/PLGA scaffolds, and their osteogenic effect and bone formation were compared systemically. At 7 days after seeding, osteogenisis was significantly increased on PLGA scaffolds containing upto 80% of DC. However, the alkaline phosphatase activity of DC/PLGA scaffolds decreased gradually after the first week and reached to the basal line after 14 days. This result indicates that DC/PLGA hybrid scaffolds are helpful for initial bone formation and differentiation, and have a positive effect on them.
| Original language | English |
|---|---|
| Pages (from-to) | 846-851 |
| Number of pages | 6 |
| Journal | Polymer (Korea) |
| Volume | 39 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2015.11 |
Keywords
- Bone marrow mesenchymal stem cells (BMSC)
- Bone reconstruction
- Bone regeneration
- Collagen
- Ducks collagen
- PLGA scaffold
Quacquarelli Symonds(QS) Subject Topics
- Materials Science
- Engineering - Chemical
Fingerprint
Dive into the research topics of 'Osteogenic effect of hybrid scaffolds composed of duck feet collagen and PLGA'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver