p-Terphenyls from the fruiting bodies of Paxillus curtisii and their antioxidant properties

In Kyoung Lee; Jin Young Jung; Young Sook Kim; Man Hee Rhee; Bong Sik Yun

doi:10.1016/j.bmc.2009.04.064

p-Terphenyls from the fruiting bodies of Paxillus curtisii and their antioxidant properties

In Kyoung Lee
, Jin Young Jung
, Young Sook Kim
, Man Hee Rhee
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Research output: Contribution to journal › Journal article › peer-review

40 Scopus citations

Abstract

New p-terphenyls, curtisians R (1)-V (5), have been isolated together with known compounds, curtisians E, I-P, and kynapcin-12, from the methanolic extract of the fruiting bodies of Paxillus curtisii (Paxillaceace). Their structures were established by various spectroscopic analyses including 1D- and 2D-NMR experiments, as well as high-resolution FAB-mass analysis. They exhibited significant protective effects against oxidative damage of supercoiled DNA and 2-deoxyribose by hydroxyl radicals generated from the Fenton reaction.

Original language	English
Pages (from-to)	4674-4680
Number of pages	7
Journal	Bioorganic and Medicinal Chemistry
Volume	17
Issue number	13
DOIs	https://doi.org/10.1016/j.bmc.2009.04.064
State	Published - 2009.07.1

Keywords

Curtisians
Fenton reaction
Free radical scavengers
p-Terphenyls
Paxillus curtisii

Quacquarelli Symonds(QS) Subject Topics

Medicine
Engineering - Petroleum
Pharmacy & Pharmacology
Chemistry
Biological Sciences

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10.1016/j.bmc.2009.04.064

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@article{807ebf4de1e343e991ee74465d70ba07,

title = "p-Terphenyls from the fruiting bodies of Paxillus curtisii and their antioxidant properties",

abstract = "New p-terphenyls, curtisians R (1)-V (5), have been isolated together with known compounds, curtisians E, I-P, and kynapcin-12, from the methanolic extract of the fruiting bodies of Paxillus curtisii (Paxillaceace). Their structures were established by various spectroscopic analyses including 1D- and 2D-NMR experiments, as well as high-resolution FAB-mass analysis. They exhibited significant protective effects against oxidative damage of supercoiled DNA and 2-deoxyribose by hydroxyl radicals generated from the Fenton reaction.",

keywords = "Curtisians, Fenton reaction, Free radical scavengers, p-Terphenyls, Paxillus curtisii",

author = "Lee, \{In Kyoung\} and Jung, \{Jin Young\} and Kim, \{Young Sook\} and Rhee, \{Man Hee\} and Yun, \{Bong Sik\}",

year = "2009",

month = jul,

day = "1",

doi = "10.1016/j.bmc.2009.04.064",

language = "English",

volume = "17",

pages = "4674--4680",

journal = "Bioorganic and Medicinal Chemistry",

issn = "0968-0896",

number = "13",

}

TY - JOUR

T1 - p-Terphenyls from the fruiting bodies of Paxillus curtisii and their antioxidant properties

AU - Lee, In Kyoung

AU - Jung, Jin Young

AU - Kim, Young Sook

AU - Rhee, Man Hee

AU - Yun, Bong Sik

PY - 2009/7/1

Y1 - 2009/7/1

N2 - New p-terphenyls, curtisians R (1)-V (5), have been isolated together with known compounds, curtisians E, I-P, and kynapcin-12, from the methanolic extract of the fruiting bodies of Paxillus curtisii (Paxillaceace). Their structures were established by various spectroscopic analyses including 1D- and 2D-NMR experiments, as well as high-resolution FAB-mass analysis. They exhibited significant protective effects against oxidative damage of supercoiled DNA and 2-deoxyribose by hydroxyl radicals generated from the Fenton reaction.

AB - New p-terphenyls, curtisians R (1)-V (5), have been isolated together with known compounds, curtisians E, I-P, and kynapcin-12, from the methanolic extract of the fruiting bodies of Paxillus curtisii (Paxillaceace). Their structures were established by various spectroscopic analyses including 1D- and 2D-NMR experiments, as well as high-resolution FAB-mass analysis. They exhibited significant protective effects against oxidative damage of supercoiled DNA and 2-deoxyribose by hydroxyl radicals generated from the Fenton reaction.

KW - Curtisians

KW - Fenton reaction

KW - Free radical scavengers

KW - p-Terphenyls

KW - Paxillus curtisii

UR - https://www.scopus.com/pages/publications/66449093814

U2 - 10.1016/j.bmc.2009.04.064

DO - 10.1016/j.bmc.2009.04.064

M3 - Journal article

C2 - 19450986

AN - SCOPUS:66449093814

SN - 0968-0896

VL - 17

SP - 4674

EP - 4680

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 13

ER -

p-Terphenyls from the fruiting bodies of Paxillus curtisii and their antioxidant properties

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

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