pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

Gyu Ha Hwang; Kyung Hyun Min; Hong Jae Lee; Hye Young Nam; Gi Hyun Choi; Byung Joo Kim; Seo Young Jeong; Sang Cheon Lee

doi:10.1039/c4cc01584c

pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

Gyu Ha Hwang
, Kyung Hyun Min
, Hong Jae Lee
, Hye Young Nam
, Gi Hyun Choi
, Byung Joo Kim
, Seo Young Jeong
, Sang Cheon Lee^*

^*Corresponding author for this work

Department of Pharmacy

Kyung Hee University

Research output: Contribution to journal › Journal article › peer-review

57 Scopus citations

Abstract

We report on pH-responsive core-shell polymer micelles with catechol-Fe³⁺ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

Original language	English
Pages (from-to)	4351-4353
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	33
DOIs	https://doi.org/10.1039/c4cc01584c
State	Published - 2014.03.27

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10.1039/c4cc01584c

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@article{acd30eadc4a04b518d92407433d3deae,

title = "pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links",

abstract = "We report on pH-responsive core-shell polymer micelles with catechol-Fe3+ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.",

author = "Hwang, \{Gyu Ha\} and Min, \{Kyung Hyun\} and Lee, \{Hong Jae\} and Nam, \{Hye Young\} and Choi, \{Gi Hyun\} and Kim, \{Byung Joo\} and Jeong, \{Seo Young\} and Lee, \{Sang Cheon\}",

year = "2014",

month = mar,

day = "27",

doi = "10.1039/c4cc01584c",

language = "English",

volume = "50",

pages = "4351--4353",

journal = "Chemical Communications",

issn = "1359-7345",

number = "33",

}

TY - JOUR

T1 - pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

AU - Hwang, Gyu Ha

AU - Min, Kyung Hyun

AU - Lee, Hong Jae

AU - Nam, Hye Young

AU - Choi, Gi Hyun

AU - Kim, Byung Joo

AU - Jeong, Seo Young

AU - Lee, Sang Cheon

PY - 2014/3/27

Y1 - 2014/3/27

N2 - We report on pH-responsive core-shell polymer micelles with catechol-Fe3+ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

AB - We report on pH-responsive core-shell polymer micelles with catechol-Fe3+ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

UR - https://www.scopus.com/pages/publications/84897132086

U2 - 10.1039/c4cc01584c

DO - 10.1039/c4cc01584c

M3 - Journal article

C2 - 24643304

AN - SCOPUS:84897132086

SN - 1359-7345

VL - 50

SP - 4351

EP - 4353

JO - Chemical Communications

JF - Chemical Communications

IS - 33

ER -

pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

Abstract

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