Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles

Loganathan Praburaman; Jum Suk Jang; Govarthanan Muthusamy; Sengottaiyan Arumugam; Koildhasan Manoharan; Kwang Min Cho; Cho Min; Seralathan Kamala-Kannan; Oh Byung-Taek

doi:10.3109/21691401.2015.1029630

Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles

Loganathan Praburaman
, Jum Suk Jang
, Govarthanan Muthusamy
, Sengottaiyan Arumugam
, Koildhasan Manoharan
, Kwang Min Cho
, Cho Min
, Seralathan Kamala-Kannan^*
, Oh Byung-Taek

^*Corresponding author for this work

Environmental Biotechnology

Jeonbuk National University
Periyar University
United States Food and Drug Administration

Research output: Contribution to journal › Journal article › peer-review

35 Scopus citations

Abstract

The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV–visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50–100 nm. The scanning electron microscopy (SEM)–energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94% at 300 μg/mL.

Original language	English
Pages (from-to)	1400-1405
Number of pages	6
Journal	Artificial Cells, Nanomedicine and Biotechnology
Volume	44
Issue number	6
DOIs	https://doi.org/10.3109/21691401.2015.1029630
State	Published - 2016.08.17

Keywords

antibacterial activity
cytotoxicity
hemolysis
phytopathogens
piper betle

Quacquarelli Symonds(QS) Subject Topics

Medicine
Pharmacy & Pharmacology
Biological Sciences

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10.3109/21691401.2015.1029630

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Praburaman, L., Jang, J. S., Muthusamy, G., Arumugam, S., Manoharan, K., Cho, K. M., Min, C., Kamala-Kannan, S., & Byung-Taek, O. (2016). Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles. Artificial Cells, Nanomedicine and Biotechnology, 44(6), 1400-1405. https://doi.org/10.3109/21691401.2015.1029630

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title = "Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles",

abstract = "The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV–visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50–100 nm. The scanning electron microscopy (SEM)–energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94\% at 300 μg/mL.",

keywords = "antibacterial activity, cytotoxicity, hemolysis, phytopathogens, piper betle",

author = "Loganathan Praburaman and Jang, \{Jum Suk\} and Govarthanan Muthusamy and Sengottaiyan Arumugam and Koildhasan Manoharan and Cho, \{Kwang Min\} and Cho Min and Seralathan Kamala-Kannan and Oh Byung-Taek",

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year = "2016",

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day = "17",

doi = "10.3109/21691401.2015.1029630",

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Praburaman, L, Jang, JS, Muthusamy, G, Arumugam, S, Manoharan, K, Cho, KM, Min, C, Kamala-Kannan, S & Byung-Taek, O 2016, 'Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles', Artificial Cells, Nanomedicine and Biotechnology, vol. 44, no. 6, pp. 1400-1405. https://doi.org/10.3109/21691401.2015.1029630

Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles. / Praburaman, Loganathan; Jang, Jum Suk; Muthusamy, Govarthanan et al.
In: Artificial Cells, Nanomedicine and Biotechnology, Vol. 44, No. 6, 17.08.2016, p. 1400-1405.

Research output: Contribution to journal › Journal article › peer-review

TY - JOUR

T1 - Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles

AU - Praburaman, Loganathan

AU - Jang, Jum Suk

AU - Muthusamy, Govarthanan

AU - Arumugam, Sengottaiyan

AU - Manoharan, Koildhasan

AU - Cho, Kwang Min

AU - Min, Cho

AU - Kamala-Kannan, Seralathan

AU - Byung-Taek, Oh

PY - 2016/8/17

Y1 - 2016/8/17

N2 - The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV–visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50–100 nm. The scanning electron microscopy (SEM)–energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94% at 300 μg/mL.

AB - The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV–visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50–100 nm. The scanning electron microscopy (SEM)–energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94% at 300 μg/mL.

KW - antibacterial activity

KW - cytotoxicity

KW - hemolysis

KW - phytopathogens

KW - piper betle

UR - https://www.scopus.com/pages/publications/84982988008

U2 - 10.3109/21691401.2015.1029630

DO - 10.3109/21691401.2015.1029630

M3 - Journal article

C2 - 26148178

AN - SCOPUS:84982988008

SN - 2169-1401

VL - 44

SP - 1400

EP - 1405

JO - Artificial Cells, Nanomedicine and Biotechnology

JF - Artificial Cells, Nanomedicine and Biotechnology

IS - 6

ER -

Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

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