Polymer-supported pentaethylene glycol as a facile heterogeneous catalyst for nucleophilic fluorination

Vinod H. Jadhav; Seung Ho Jang; Hwan Jeong Jeong; Seok Tae Lim; Myung Hee Sohn; Dae Yoon Chi; Dong Wook Kim

doi:10.1021/ol101485n

Polymer-supported pentaethylene glycol as a facile heterogeneous catalyst for nucleophilic fluorination

Vinod H. Jadhav
, Seung Ho Jang
, Hwan Jeong Jeong
, Seok Tae Lim
, Myung Hee Sohn
, Dae Yoon Chi
, Dong Wook Kim

Department of Medicine

Research output: Contribution to journal › Journal article › peer-review

35 Scopus citations

Abstract

Polymer-supported pentaethylene glycols (PSpentaEG) as promising catalysts for nucleophilic fluorination with alkali metal fluoride (MF) could significantly enhance the nucleophilicity of MF and provide simple purification and recycling in the reaction. Furthermore, by their synergistic effect, the combination of PSpentaEG and a tert-alcohol media system showed tremendous efficiency in the fluorination of base-sensitive substrates such as sec-alkyl halide.

Original language	English
Pages (from-to)	3740-3743
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	17
DOIs	https://doi.org/10.1021/ol101485n
State	Published - 2010.09.3

Quacquarelli Symonds(QS) Subject Topics

Engineering - Petroleum
Chemistry
Biological Sciences

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10.1021/ol101485n

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title = "Polymer-supported pentaethylene glycol as a facile heterogeneous catalyst for nucleophilic fluorination",

abstract = "Polymer-supported pentaethylene glycols (PSpentaEG) as promising catalysts for nucleophilic fluorination with alkali metal fluoride (MF) could significantly enhance the nucleophilicity of MF and provide simple purification and recycling in the reaction. Furthermore, by their synergistic effect, the combination of PSpentaEG and a tert-alcohol media system showed tremendous efficiency in the fluorination of base-sensitive substrates such as sec-alkyl halide.",

author = "Jadhav, \{Vinod H.\} and Jang, \{Seung Ho\} and Jeong, \{Hwan Jeong\} and Lim, \{Seok Tae\} and Sohn, \{Myung Hee\} and Chi, \{Dae Yoon\} and Kim, \{Dong Wook\}",

year = "2010",

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doi = "10.1021/ol101485n",

language = "English",

volume = "12",

pages = "3740--3743",

journal = "Organic Letters",

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T1 - Polymer-supported pentaethylene glycol as a facile heterogeneous catalyst for nucleophilic fluorination

AU - Jadhav, Vinod H.

AU - Jang, Seung Ho

AU - Jeong, Hwan Jeong

AU - Lim, Seok Tae

AU - Sohn, Myung Hee

AU - Chi, Dae Yoon

AU - Kim, Dong Wook

PY - 2010/9/3

Y1 - 2010/9/3

N2 - Polymer-supported pentaethylene glycols (PSpentaEG) as promising catalysts for nucleophilic fluorination with alkali metal fluoride (MF) could significantly enhance the nucleophilicity of MF and provide simple purification and recycling in the reaction. Furthermore, by their synergistic effect, the combination of PSpentaEG and a tert-alcohol media system showed tremendous efficiency in the fluorination of base-sensitive substrates such as sec-alkyl halide.

AB - Polymer-supported pentaethylene glycols (PSpentaEG) as promising catalysts for nucleophilic fluorination with alkali metal fluoride (MF) could significantly enhance the nucleophilicity of MF and provide simple purification and recycling in the reaction. Furthermore, by their synergistic effect, the combination of PSpentaEG and a tert-alcohol media system showed tremendous efficiency in the fluorination of base-sensitive substrates such as sec-alkyl halide.

UR - https://www.scopus.com/pages/publications/77956206310

U2 - 10.1021/ol101485n

DO - 10.1021/ol101485n

M3 - Journal article

C2 - 20684535

AN - SCOPUS:77956206310

SN - 1523-7060

VL - 12

SP - 3740

EP - 3743

JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

Polymer-supported pentaethylene glycol as a facile heterogeneous catalyst for nucleophilic fluorination

Abstract

Quacquarelli Symonds(QS) Subject Topics

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