Preparation of polyethyleneglycol and polycaprolactone block copolymers and their biomedical applications

Large numbers of research groups have recently been focused on the preparation of block copolymers based on PEG. Considering the practical application of these block copolymers to biomedical research, it would be beneficial if the molecular design of block segments could be understood from the perspective of the phase transition. This work will focus on the preparation and characterization of various PEG and polyester block copolymers with a variety of segments and the examination of the phase transition behaviors according to the changes in the segments to understand how the copolymer composition influences the phase transition. Further biomedical application will present to state the possibility of these block copolymers as a drug carrier and scaffold in tissue engineering via in situ gel formation.