Quantitative analysis comparison of Korea and China Scrophulariae Radix

Hye Won Lee; So Young Park; Byung Kil Choo; Jin Mi Chun; AYeong Lee; Ho Kyoung Kim

Quantitative analysis comparison of Korea and China Scrophulariae Radix

Hye Won Lee^*
, So Young Park
, Byung Kil Choo
, Jin Mi Chun
, AYeong Lee
, Ho Kyoung Kim

^*Corresponding author for this work

Department of Crop Agriculture and Life Science

Korea Institute of Oriental Medicine

Research output: Contribution to journal › Journal article › peer-review

2 Scopus citations

Abstract

Scrophulariae Radix (Scrophulariaceae) is a perennial growing in all parts of Korea, China and Asia. It has been used as a folk medicine in treating guttural diseases acting as an antiphlogistics, antipyretics and analgesics. In this report, to compare with Korea and China product, quantitative analysis of harpagoside and p-methoxy cinnamic acid (4-MCA) was performed by HPLC method. Using a Luna C₁₈(2) column, we carried out quantitative analysis with 0.1% phosphoric acid in water and acetonitrile as gradient condition. Harpagoside and 4-MCA were detected at retention time of about 11.5 and 15.0 min, respectively. Contents of harpagoside and 4-MCA proved that Korean products were higher than China more than twice.

Original language	English
Pages (from-to)	15-18
Number of pages	4
Journal	Korean Journal of Pharmacognosy
Volume	38
Issue number	1
State	Published - 2007.03

Keywords

Harpagoside
HPLC
p-methoxycinnamic acid (4-MCA)
Scrophulariaceae
Scrophulariae Radix

Cite this

@article{a6ccf42f4a4b412897cfbb32613ac9bc,

title = "Quantitative analysis comparison of Korea and China Scrophulariae Radix",

abstract = "Scrophulariae Radix (Scrophulariaceae) is a perennial growing in all parts of Korea, China and Asia. It has been used as a folk medicine in treating guttural diseases acting as an antiphlogistics, antipyretics and analgesics. In this report, to compare with Korea and China product, quantitative analysis of harpagoside and p-methoxy cinnamic acid (4-MCA) was performed by HPLC method. Using a Luna C18(2) column, we carried out quantitative analysis with 0.1\% phosphoric acid in water and acetonitrile as gradient condition. Harpagoside and 4-MCA were detected at retention time of about 11.5 and 15.0 min, respectively. Contents of harpagoside and 4-MCA proved that Korean products were higher than China more than twice.",

keywords = "Harpagoside, HPLC, p-methoxycinnamic acid (4-MCA), Scrophulariaceae, Scrophulariae Radix",

author = "Lee, \{Hye Won\} and Park, \{So Young\} and Choo, \{Byung Kil\} and Chun, \{Jin Mi\} and AYeong Lee and Kim, \{Ho Kyoung\}",

year = "2007",

month = mar,

language = "English",

volume = "38",

pages = "15--18",

journal = "Korean Journal of Pharmacognosy",

issn = "0253-3073",

number = "1",

}

TY - JOUR

T1 - Quantitative analysis comparison of Korea and China Scrophulariae Radix

AU - Lee, Hye Won

AU - Park, So Young

AU - Choo, Byung Kil

AU - Chun, Jin Mi

AU - Lee, AYeong

AU - Kim, Ho Kyoung

PY - 2007/3

Y1 - 2007/3

N2 - Scrophulariae Radix (Scrophulariaceae) is a perennial growing in all parts of Korea, China and Asia. It has been used as a folk medicine in treating guttural diseases acting as an antiphlogistics, antipyretics and analgesics. In this report, to compare with Korea and China product, quantitative analysis of harpagoside and p-methoxy cinnamic acid (4-MCA) was performed by HPLC method. Using a Luna C18(2) column, we carried out quantitative analysis with 0.1% phosphoric acid in water and acetonitrile as gradient condition. Harpagoside and 4-MCA were detected at retention time of about 11.5 and 15.0 min, respectively. Contents of harpagoside and 4-MCA proved that Korean products were higher than China more than twice.

AB - Scrophulariae Radix (Scrophulariaceae) is a perennial growing in all parts of Korea, China and Asia. It has been used as a folk medicine in treating guttural diseases acting as an antiphlogistics, antipyretics and analgesics. In this report, to compare with Korea and China product, quantitative analysis of harpagoside and p-methoxy cinnamic acid (4-MCA) was performed by HPLC method. Using a Luna C18(2) column, we carried out quantitative analysis with 0.1% phosphoric acid in water and acetonitrile as gradient condition. Harpagoside and 4-MCA were detected at retention time of about 11.5 and 15.0 min, respectively. Contents of harpagoside and 4-MCA proved that Korean products were higher than China more than twice.

KW - Harpagoside

KW - HPLC

KW - p-methoxycinnamic acid (4-MCA)

KW - Scrophulariaceae

KW - Scrophulariae Radix

UR - https://www.scopus.com/pages/publications/34247144982

M3 - Journal article

AN - SCOPUS:34247144982

SN - 0253-3073

VL - 38

SP - 15

EP - 18

JO - Korean Journal of Pharmacognosy

JF - Korean Journal of Pharmacognosy

IS - 1

ER -

Quantitative analysis comparison of Korea and China Scrophulariae Radix

Abstract

Keywords

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