Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug

S. V. Berwin Singh; Angela Guma Adam; Nirmalya Tripathy; Dongwon Lee; Gilson Khang

doi:10.1007/978-981-13-0950-2_15

Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug

S. V. Berwin Singh
, Angela Guma Adam
, Nirmalya Tripathy
, Dongwon Lee
, Gilson Khang^*

^*Corresponding author for this work

Department of Polymer -Nano Science &Technology

Jeonbuk National University
Moringa Connect Company
University of Washington

Research output: Contribution to conference › Chapter › peer-review

6 Scopus citations

Abstract

Reactive Oxygen Species (ROS) play a vital role in the biological system. Exaggerated, ROS have devastating effects on the human body leading to the pathophysiological condition including the transformation of a normal cell into a cancer phenotype. Nature has blessed us with various biomolecules that we use along with our dietary supplements. Using such therapeutic small molecules covalently incorporated into biodegradable polyoxalate polymer backbone with a responsive group forms an efficient drug delivery vehicle. This chapter “Reactive oxygen species responsive naturally occurring phenolic-based polymeric prodrug” will be focusing on redox-responsive polymers incorporated with naturally occurring phenolics and clinical application.

Original language	English
Title of host publication	Advances in Experimental Medicine and Biology
Publisher	Springer New York LLC
Pages	291-301
Number of pages	11
DOIs	https://doi.org/10.1007/978-981-13-0950-2_15
State	Published - 2018

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	1078
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Polyoxalate polymers
Prodrug
Reactive oxygen species
Redox responsive polymers

Quacquarelli Symonds(QS) Subject Topics

Biological Sciences

Access to Document

10.1007/978-981-13-0950-2_15

Cite this

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title = "Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug",

abstract = "Reactive Oxygen Species (ROS) play a vital role in the biological system. Exaggerated, ROS have devastating effects on the human body leading to the pathophysiological condition including the transformation of a normal cell into a cancer phenotype. Nature has blessed us with various biomolecules that we use along with our dietary supplements. Using such therapeutic small molecules covalently incorporated into biodegradable polyoxalate polymer backbone with a responsive group forms an efficient drug delivery vehicle. This chapter “Reactive oxygen species responsive naturally occurring phenolic-based polymeric prodrug” will be focusing on redox-responsive polymers incorporated with naturally occurring phenolics and clinical application.",

keywords = "Polyoxalate polymers, Prodrug, Reactive oxygen species, Redox responsive polymers",

author = "\{Berwin Singh\}, \{S. V.\} and Adam, \{Angela Guma\} and Nirmalya Tripathy and Dongwon Lee and Gilson Khang",

note = "Publisher Copyright: {\textcopyright} 2018, Springer Nature Singapore Pte Ltd.",

year = "2018",

doi = "10.1007/978-981-13-0950-2\_15",

language = "English",

series = "Advances in Experimental Medicine and Biology",

publisher = "Springer New York LLC",

pages = "291--301",

booktitle = "Advances in Experimental Medicine and Biology",

}

Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug. / Berwin Singh, S. V.; Adam, Angela Guma; Tripathy, Nirmalya et al.
Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. p. 291-301 (Advances in Experimental Medicine and Biology; Vol. 1078).

Research output: Contribution to conference › Chapter › peer-review

TY - CHAP

T1 - Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug

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AU - Adam, Angela Guma

AU - Tripathy, Nirmalya

AU - Lee, Dongwon

AU - Khang, Gilson

PY - 2018

Y1 - 2018

N2 - Reactive Oxygen Species (ROS) play a vital role in the biological system. Exaggerated, ROS have devastating effects on the human body leading to the pathophysiological condition including the transformation of a normal cell into a cancer phenotype. Nature has blessed us with various biomolecules that we use along with our dietary supplements. Using such therapeutic small molecules covalently incorporated into biodegradable polyoxalate polymer backbone with a responsive group forms an efficient drug delivery vehicle. This chapter “Reactive oxygen species responsive naturally occurring phenolic-based polymeric prodrug” will be focusing on redox-responsive polymers incorporated with naturally occurring phenolics and clinical application.

AB - Reactive Oxygen Species (ROS) play a vital role in the biological system. Exaggerated, ROS have devastating effects on the human body leading to the pathophysiological condition including the transformation of a normal cell into a cancer phenotype. Nature has blessed us with various biomolecules that we use along with our dietary supplements. Using such therapeutic small molecules covalently incorporated into biodegradable polyoxalate polymer backbone with a responsive group forms an efficient drug delivery vehicle. This chapter “Reactive oxygen species responsive naturally occurring phenolic-based polymeric prodrug” will be focusing on redox-responsive polymers incorporated with naturally occurring phenolics and clinical application.

KW - Polyoxalate polymers

KW - Prodrug

KW - Reactive oxygen species

KW - Redox responsive polymers

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M3 - Chapter

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AN - SCOPUS:85055596270

T3 - Advances in Experimental Medicine and Biology

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BT - Advances in Experimental Medicine and Biology

PB - Springer New York LLC

ER -

Reactive Oxygen Species Responsive Naturally Occurring Phenolic-Based Polymeric Prodrug

Abstract

Publication series

UN SDGs

Keywords

Quacquarelli Symonds(QS) Subject Topics

Access to Document

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