Real time monitoring of the biocompatibility behavior of modified titanium oxide surfaces using Electrochemical Quartz Crystal Nanobalance (EQCN)

In this study, the biological interaction of a diversely modified three different Titanium (Ti) surfaces was analyzed using EQCN. EQCN was used to monitor the adhesion of bacteria on the Ti surfaces. The adherence of Escherichia coli and Staphylococcus aureus bacteria were continuously monitored by the changes in the resonant frequency (Δf) of EQCN. The biocompatibilities of the surfaces were directly measured by correlating the attachment rate of bacteria on the surfaces. The results state that, among the surface modification techniques employed in the study, electrochemical adonization is a potential method to modify the material surfaces for biomedical application.