Recent advances in graphene-based biosensors

Tapas Kuila; Saswata Bose; Partha Khanra; Ananta Kumar Mishra; Nam Hoon Kim; Joong Hee Lee

doi:10.1016/j.bios.2011.05.039

Recent advances in graphene-based biosensors

Tapas Kuila
, Saswata Bose
, Partha Khanra
, Ananta Kumar Mishra
, Nam Hoon Kim
, Joong Hee Lee^*

^*Corresponding author for this work

Department of Nano Convergence Engineering

Jeonbuk National University

Research output: Contribution to journal › Review article › peer-review

1275 Scopus citations

Abstract

A detailed overview towards the advancement of graphene based biosensors has been reviewed. The large surface area and excellent electrical conductivity of graphene allow it to act as an " electron wire" between the redox centers of an enzyme or protein and an electrode's surface. Rapid electron transfer facilitates accurate and selective detection of biomolecules. This review discusses the application of graphene for the detection of glucose, Cyt-c, NADH, Hb, cholesterol, AA, UA, DA, and H ₂O ₂. GO and RGO have been used for the fabrication of heavy metal ion sensors, gas sensors, and DNA sensors. Graphene based FETs have also been discussed in details. In all these cases, the biosensors performed well with low working potentials, high sensitivities, low detection limits, and long-term stabilities.

Original language	English
Pages (from-to)	4637-4648
Number of pages	12
Journal	Biosensors and Bioelectronics
Volume	26
Issue number	12
DOIs	https://doi.org/10.1016/j.bios.2011.05.039
State	Published - 2011.08.15

Keywords

Biocompatibility
DNA sensor
Enzyme biosensor
Gas sensor
Graphene
Graphene electrode

Quacquarelli Symonds(QS) Subject Topics

Chemistry
Biological Sciences

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10.1016/j.bios.2011.05.039

Cite this

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title = "Recent advances in graphene-based biosensors",

abstract = "A detailed overview towards the advancement of graphene based biosensors has been reviewed. The large surface area and excellent electrical conductivity of graphene allow it to act as an {"} electron wire{"} between the redox centers of an enzyme or protein and an electrode's surface. Rapid electron transfer facilitates accurate and selective detection of biomolecules. This review discusses the application of graphene for the detection of glucose, Cyt-c, NADH, Hb, cholesterol, AA, UA, DA, and H 2O 2. GO and RGO have been used for the fabrication of heavy metal ion sensors, gas sensors, and DNA sensors. Graphene based FETs have also been discussed in details. In all these cases, the biosensors performed well with low working potentials, high sensitivities, low detection limits, and long-term stabilities.",

keywords = "Biocompatibility, DNA sensor, Enzyme biosensor, Gas sensor, Graphene, Graphene electrode",

author = "Tapas Kuila and Saswata Bose and Partha Khanra and Mishra, \{Ananta Kumar\} and Kim, \{Nam Hoon\} and Lee, \{Joong Hee\}",

year = "2011",

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day = "15",

doi = "10.1016/j.bios.2011.05.039",

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AU - Kuila, Tapas

AU - Bose, Saswata

AU - Khanra, Partha

AU - Mishra, Ananta Kumar

AU - Kim, Nam Hoon

AU - Lee, Joong Hee

PY - 2011/8/15

Y1 - 2011/8/15

N2 - A detailed overview towards the advancement of graphene based biosensors has been reviewed. The large surface area and excellent electrical conductivity of graphene allow it to act as an " electron wire" between the redox centers of an enzyme or protein and an electrode's surface. Rapid electron transfer facilitates accurate and selective detection of biomolecules. This review discusses the application of graphene for the detection of glucose, Cyt-c, NADH, Hb, cholesterol, AA, UA, DA, and H 2O 2. GO and RGO have been used for the fabrication of heavy metal ion sensors, gas sensors, and DNA sensors. Graphene based FETs have also been discussed in details. In all these cases, the biosensors performed well with low working potentials, high sensitivities, low detection limits, and long-term stabilities.

AB - A detailed overview towards the advancement of graphene based biosensors has been reviewed. The large surface area and excellent electrical conductivity of graphene allow it to act as an " electron wire" between the redox centers of an enzyme or protein and an electrode's surface. Rapid electron transfer facilitates accurate and selective detection of biomolecules. This review discusses the application of graphene for the detection of glucose, Cyt-c, NADH, Hb, cholesterol, AA, UA, DA, and H 2O 2. GO and RGO have been used for the fabrication of heavy metal ion sensors, gas sensors, and DNA sensors. Graphene based FETs have also been discussed in details. In all these cases, the biosensors performed well with low working potentials, high sensitivities, low detection limits, and long-term stabilities.

KW - Biocompatibility

KW - DNA sensor

KW - Enzyme biosensor

KW - Gas sensor

KW - Graphene

KW - Graphene electrode

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U2 - 10.1016/j.bios.2011.05.039

DO - 10.1016/j.bios.2011.05.039

M3 - Review article

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AN - SCOPUS:79960452977

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JO - Biosensors and Bioelectronics

JF - Biosensors and Bioelectronics

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ER -

Recent advances in graphene-based biosensors

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

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