(S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery

Sankarprasad Bhuniya; Young Jun Seo; Byeang Hyean Kim

doi:10.1016/j.tetlet.2006.08.002

(S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery

Sankarprasad Bhuniya
, Young Jun Seo
, Byeang Hyean Kim^*

^*Corresponding author for this work

Department of Chemistry

National Research Laboratory

Research output: Contribution to journal › Journal article › peer-review

79 Scopus citations

Abstract

We have synthesized (S)-(+)-ibuprofen-based hydrogelators that feature dipeptide linkages. In aqueous media, one of these hydrogelators formed robust gels that were stable for several months. Enzyme-mediated hydrolysis offers a route toward the sustained release of this anti-inflammatory agent.

Original language	English
Pages (from-to)	7153-7156
Number of pages	4
Journal	Tetrahedron Letters
Volume	47
Issue number	40
DOIs	https://doi.org/10.1016/j.tetlet.2006.08.002
State	Published - 2006.10.2

Keywords

Anti-inflammatory
Hydrogelator
Self-delivery

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10.1016/j.tetlet.2006.08.002

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@article{a202600b1b90408192a7c60af61e0d10,

title = "(S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery",

abstract = "We have synthesized (S)-(+)-ibuprofen-based hydrogelators that feature dipeptide linkages. In aqueous media, one of these hydrogelators formed robust gels that were stable for several months. Enzyme-mediated hydrolysis offers a route toward the sustained release of this anti-inflammatory agent.",

keywords = "Anti-inflammatory, Hydrogelator, Self-delivery",

author = "Sankarprasad Bhuniya and Seo, \{Young Jun\} and Kim, \{Byeang Hyean\}",

year = "2006",

month = oct,

day = "2",

doi = "10.1016/j.tetlet.2006.08.002",

language = "English",

volume = "47",

pages = "7153--7156",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "40",

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TY - JOUR

T1 - (S)-(+)-Ibuprofen-based hydrogelators

T2 - an approach toward anti-inflammatory drug delivery

AU - Bhuniya, Sankarprasad

AU - Seo, Young Jun

AU - Kim, Byeang Hyean

PY - 2006/10/2

Y1 - 2006/10/2

N2 - We have synthesized (S)-(+)-ibuprofen-based hydrogelators that feature dipeptide linkages. In aqueous media, one of these hydrogelators formed robust gels that were stable for several months. Enzyme-mediated hydrolysis offers a route toward the sustained release of this anti-inflammatory agent.

AB - We have synthesized (S)-(+)-ibuprofen-based hydrogelators that feature dipeptide linkages. In aqueous media, one of these hydrogelators formed robust gels that were stable for several months. Enzyme-mediated hydrolysis offers a route toward the sustained release of this anti-inflammatory agent.

KW - Anti-inflammatory

KW - Hydrogelator

KW - Self-delivery

UR - https://www.scopus.com/pages/publications/33747888318

U2 - 10.1016/j.tetlet.2006.08.002

DO - 10.1016/j.tetlet.2006.08.002

M3 - Journal article

AN - SCOPUS:33747888318

SN - 0040-4039

VL - 47

SP - 7153

EP - 7156

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 40

ER -

(S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery

Abstract

Keywords

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