Abstract
Background: The sequential occurrence of the 2 malignancies development of nasopharyngeal carcinoma (NPC) and lymphoma is extremely rare and their coexistence raises the question of a common etiologic factor. Clinical findings/clinical concerns: A 71-year-old previously healthy man presented with diffuse large B-cell lymphoma (BCL) followed by NPC almost 2 years later with Epstein-Barr virus (EBV) positive. Diagnosis: Endoscopic examination characterized a fixed, hard and nontender mass in the nasopharynx and biopsies were done. Intervention: A patient successfully underwent chemotherapy for lymphoma and chemoradiation for carcinoma sequentially. Outcomes: He was followed up every 3 months for 1 year with endoscopic and radiological examinations. The nasopharynx mass was completely resolved after chemoradiation therapy. Conclusion: The presentation with diffuse large B-cell lymphoma (BCL) and NPC in this patient was perhaps caused by dual EBV infection or a different oncogenic mechanism.
| Original language | English |
|---|---|
| Article number | 9595 |
| Journal | Medicine (United States) |
| Volume | 97 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2018.01.1 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- carcinoma
- lymphoma
- nasopharynx
Quacquarelli Symonds(QS) Subject Topics
- Medicine
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